Evidence map›Paper›PMID 27351025›Full record

ArticleInternational journal of reproductive biomedicine2016

Association study of Glutathione S-Transferase polymorphisms and risk of endometriosis in an Iranian population.

Mina Hassani, Kioomars Saliminejad, Masood Heidarizadeh, Koorosh Kamali, Toktam Memariani, Hamid Reza Khorram Khorshid

Open access · goldAbstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of reproductive biomedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Antioxidants (Basel, Switzerland) · 2023
    Article
  3. Defining the genetic profile of endometriosis.Experimental and therapeutic medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mina HassaniDepartment of Biology, Faculty of Science, University of Kurdistan, Sanandaj, Iran.
Kioomars SaliminejadReproductive Biotechnology Research Center, Avicenna Research Institute (ACECR), Tehran, Iran.
Masood HeidarizadehDepartment of Biology, Faculty of Science, University of Kurdistan, Sanandaj, Iran.
Koorosh KamaliReproductive Biotechnology Research Center, Avicenna Research Institute (ACECR), Tehran, Iran.
Toktam MemarianiCentral Research Lab, North Khorasan University of Medical Sciences, Bojnurd, Iran.
Hamid Reza Khorram KhorshidGenetic Research Center, University of Social Welfare and Rehabilitation Science, Tehran, Iran.; Avicenna Research Institute, Shahid Beheshti University, Tehran, Iran.
Academic Center for Education, Culture and Research · IRUniversity of Kurdistan · IRNorth Khorasan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndometriosis influenced by both genetic and environmental factors. Associations of glutathione S-transferases (GSTs) genes polymorphisms in endometriosis have been investigated by various researchers; however, the results are not consistent.

objectiveWe examined the associations of GSTM1 and GSTT1 null genotypes and GSTP1 313 A/G polymorphisms with endometriosis in an Iranian population. MATERIALS AND

methodsIn this case-control study, 151 women with diagnosis of endometriosis and 156 normal healthy women as control group were included. The genotyping was determined using multiplex PCR and PCR- RFLP methods.

resultsThe GSTM1 null genotype was significantly higher (p=0.027) in the cases (7.3%) than the control group (1.3%). There was no significant difference between the frequency of GSTT1 genotypes between the cases and controls. The GSTP1 313 AG genotype was significantly lower (p=0.048) in the case (33.1%) than the control group (44.4%).

conclusionOur results showed that GSTM1 and GSTP1 polymorphisms may be associated with susceptibility of endometriosis in Iranian women.

Indexed as

Association studyEndometriosisGSTM1GSTP1GSTT1Polymorphism

Identifiers

PMID27351025
PMCPMC4918774
OpenAlexW2407087092

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.