Evidence map›Paper›PMID 27350826›Full record

ReviewGenes and environment : the official journal of the Japanese Environmental Mutagen Society2016

Effects of NSAIDs on the risk factors of colorectal cancer: a mini review.

Takahiro Hamoya, Gen Fujii, Shingo Miyamoto, Mami Takahashi, Yukari Totsuka, Keiji Wakabayashi, Jiro Toshima, Michihiro Mutoh

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Genes and environment : the official journal of the Japanese Environmental Mutagen Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Takahiro HamoyaEpidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku Tokyo, 104-0045 Japan ; Department of Biological Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, , Katsusika-ku Tokyo, 125-8585 Japan.
Gen FujiiDivision of Carcinogenesis and Cancer Prevention, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku Tokyo, 104-0045 Japan.
Shingo MiyamotoEpidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku Tokyo, 104-0045 Japan.
Mami TakahashiCentral Animal Division, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku Tokyo, 104-0045 Japan.
Yukari TotsukaDivision of Carcinogenesis and Cancer Prevention, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku Tokyo, 104-0045 Japan.
Keiji WakabayashiGraduate Division of Nutritional and Environmental Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku Shizuoka, 422-8526 Japan.
Jiro ToshimaDepartment of Biological Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, , Katsusika-ku Tokyo, 125-8585 Japan.
Michihiro MutohEpidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku Tokyo, 104-0045 Japan ; Division of Carcinogenesis and Cancer Prevention, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku Tokyo, 104-0045 Japan.
National Cancer Centre Japan · JPTokyo University of Science · JPUniversity of Shizuoka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence from epidemiological and experimental studies has shown that non-steroidal anti-inflammatory drugs (NSAIDs) reduce the risk of colorectal cancer (CRC). The function of NSAIDs and the molecular targets for chemopreventive effects on CRC have been extensively studied and their data were reported. However, the relation between NSAIDs and the risk factors of CRC have not been fully elucidated yet. Thus, relations between NSAIDs and the risk factors of CRC, such as overweight and obesity, alcohol, aging, hypertriglyceridemia and smoking, are summarized with our data and with recent reported data in this review.

Indexed as

ChemopreventionColorectal cancerNon-steroidal anti-inflammatory drugsRisk factors

Identifiers

PMID27350826
PMCPMC4918106
OpenAlexW2318312888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.