ArticleEXCLI journal2012
Prevalence of G6721T polymorphism of XRCC7 in an Iranian population.
Article in EXCLI journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Prevalence of Null Genotypes of Glutathione S-Transferase T1 (GSTT1) and M1 (GSTM1) in Seven Iranian Populations.Iranian journal of public health · 2015Article
- Association between Insertion/Deletion Polymorphism in Angiotension Converting Enzyme and Susceptibility to Schizophrenia.Iranian journal of public health · 2015Article
- Association betweenMolecular biology research communications · 2015Article
- First survey of the two polymorphisms (Arg194Trp and Arg399Gln) in XRCC1 gene in four Afghanistan populations and comparison with worldwide data.Molecular biology reports · 2013Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic polymorphism G6721T (rs.7003908) in gene encoding DNA-dependent protein kinase (DNA-PKcs, encoded by the XRCC7 gene) has been defined. In order to get more insight into the genetic structure of Iranian population the present study was carried out on Iranian Persian population living in Shiraz (Fars province, southwest Iran). The total study subjects consisted of 935 (195 males, 740 females) unrelated healthy individuals. Genotypes of XRCC7 G6721T were detected by PCR-RFLP based method. There was no significant difference between males and females for the XRCC7 polymorphism (χ(2)=1.275, df=2, P=0.529). Prevalence of the G allele was 0.473 (95 % CI: 0.441-0.505) in our sample. The study population was at Hardy-Weinberg equilibrium for the XRCC7 polymorphism (χ(2)=0.980, df=1, P=0.323). The allelic frequency of the G allele showed high frequency in Iranian population compared to other populations.
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27350771PMC4920041W2331892899What OpenQuestion holds
Registered trials
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