ArticlePediatric radiology2016
Evaluation of blood flow distribution asymmetry and vascular geometry in patients with Fontan circulation using 4-D flow MRI.
Article in Pediatric radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Pulmonary Flow Distribution in Patients Following Hemi-Mustard and Bidirectional Glenn Using Quantitative 4D Flow Particle Tracking.Journal of magnetic resonance imaging : JMRI · 2026Article
- 5D Flow MRI Reveals Respiration-Driven Changes in Blood Flow Energetics in Congenital Heart Disease.Magnetic resonance in medicine · 2026Article
- Deep learning for vessel segmentation and flow analysis to identify clusters associated with adverse outcomes in a fontan patient registry.Scientific reports · 2026Article
- Going with the flow: Implementing a 4D flow MRI program at a children's hospital.Pediatric radiology · 2025Review
- Impact of 4D-Flow CMR Parameters on Functional Evaluation of Fontan Circulation.Pediatric cardiology · 2024Article
- Flow evaluation software for four-dimensional flow MRI: a reliability and validation study.La Radiologia medica · 2023Article
- Impact of pulmonary artery flow distribution on Fontan hemodynamics and flow energetics.Pediatric radiology · 2023Article
- Fully automated intracardiac 4D flow MRI post-processing using deep learning for biventricular segmentation.European radiology · 2022Article
- Contrast-Enhanced CT Protocol for the Fontan Pathway: Comparison Between 1- and 3-Minute Scan Delays.Pediatric cardiology · 2022Article
- Additional value and new insights by four-dimensional flow magnetic resonance imaging in congenital heart disease: application in neonates and young children.Pediatric radiology · 2021Review
- Non-uniform mixing of hepatic venous flow and inferior vena cava flow in the Fontan conduit.Journal of the Royal Society, Interface · 2021Article
- Reduced scan time and superior image quality with 3D flow MRI compared to 4D flow MRI for hemodynamic evaluation of the Fontan pathway.Scientific reports · 2021Article
- 4D flow MRI applications in congenital heart disease.European radiology · 2021Review
- The Influence of Respiration on Blood Flow in the Fontan Circulation: Insights for Imaging-Based Clinical Evaluation of the Total Cavopulmonary Connection.Frontiers in cardiovascular medicine · 2021Review
- Flow profile characteristics in Fontan circulation are associated with the single ventricle dilation and function: principal component analysis study.American journal of physiology. Heart and circulatory physiology · 2020Article
- Numerical Simulation of the Effect of Pulmonary Vascular Resistance on the Hemodynamics of Reoperation After Failure of One and a Half Ventricle Repair.Frontiers in physiology · 2020Article
- Respiration Dependency of Caval Blood Flow in Patients with Fontan Circulation: Quantification Using 5D Flow MRI.Radiology. Cardiothoracic imaging · 2019Article
- Caval to pulmonary 3D flow distribution in patients with Fontan circulation and impact of potential 4D flow MRI error sources.Magnetic resonance in medicine · 2019Article
- Unravelling cardiovascular disease using four dimensional flow cardiovascular magnetic resonance.The international journal of cardiovascular imaging · 2017Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundAsymmetrical caval to pulmonary blood flow is suspected to cause complications in patients with Fontan circulation. The aim of this study was to test the feasibility of 4-D flow MRI for characterizing the relationship between 3-D blood flow distribution and vascular geometry.
objectiveWe hypothesized that both flow distribution and geometry can be calculated with low interobserver variability and will detect a direct relationship between flow distribution and Fontan geometry. MATERIALS AND
methodsFour-dimensional flow MRI was acquired in 10 Fontan patients (age: 16 ± 4 years [mean ± standard deviation], range: 9-21 years). The Fontan connection was isolated by 3-D segmentation to evaluate flow distribution from the inferior vena cava (IVC) and superior vena cava (SVC) to the left and right pulmonary arteries (LPA, RPA) and to characterize geometry (cross-sectional area, caval offset, vessel angle).
resultsFlow distribution results indicated SVC flow tended toward the RPA while IVC flow was more evenly distributed (SVC to RPA: 78% ± 28 [9-100], IVC to LPA: 54% ± 28 [4-98]). There was a significant relationship between pulmonary artery cross-sectional area and flow distribution (IVC to RPA: R(2)=0.50, P=0.02; SVC to LPA: R(2)=0.81, P=0.0004). Good agreement was found between observers and for flow distribution when compared to net flow values.
conclusionFour-dimensional flow MRI was able to detect relationships between flow distribution and vessel geometry. Future studies are warranted to investigate the potential of patient specific hemodynamic analysis to improve diagnostic capability.
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