Evidence map›Paper›PMID 27350324›Full record

ReviewMycopathologia2016

Combined Orofacial Aspergillosis and Mucormycosis: Fatal Complication of a Recurrent Paediatric Glioma-Case Report and Review of Literature.

Maddalena Chermetz, Margherita Gobbo, Katia Rupel, Giulia Ottaviani, Giancarlo Tirelli, Rossana Bussani, Roberto Luzzati, Roberto Di Lenarda, Matteo Biasotto

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Mycopathologia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. [Research progress of mucormycosis in burns].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023
    Review
  6. Article
  7. A Rare Case of MandibularDentistry journal · 2022
    Article
  8. Atypical presentations of fungal osteomyelitis during post COVID-19 outbreak - Case series.Journal of oral and maxillofacial surgery, medicine, and pathology · 2022
    Article
  9. Management of frontal sinus fungal osteomyelitis in the COVID 19 era: A case series.Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery · 2022
    Review
  10. Review
  11. Article
  12. Article
  13. Fungal Invasive Co-Infection Due toJournal of fungi (Basel, Switzerland) · 2021
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Maddalena ChermetzDivision of Oral Medicine, Dental Science Department, University of Trieste, Piazza dell'Ospitale 2, 34125, Trieste, Italy.
Margherita GobboDivision of Oral Medicine, Dental Science Department, University of Trieste, Piazza dell'Ospitale 2, 34125, Trieste, Italy.
Katia RupelDivision of Oral Medicine, Dental Science Department, University of Trieste, Piazza dell'Ospitale 2, 34125, Trieste, Italy.
Giulia OttavianiDivision of Oral Medicine, Dental Science Department, University of Trieste, Piazza dell'Ospitale 2, 34125, Trieste, Italy.
Giancarlo TirelliDepartment of Otorhinolaryngology, Head and Neck Surgery, Cattinara Hospital, Strada di Fiume 447, 34149, Trieste, Italy.
Rossana BussaniUCO Pathological Anatomy and Histopathology Unit, Cattinara Hospital, Strada di Fiume 447, 34149, Trieste, Italy.
Roberto LuzzatiInfectious Diseases Unit, University Hospital, Trieste, Italy.
Roberto Di LenardaDivision of Oral Medicine, Dental Science Department, University of Trieste, Piazza dell'Ospitale 2, 34125, Trieste, Italy.
Matteo BiasottoDivision of Oral Medicine, Dental Science Department, University of Trieste, Piazza dell'Ospitale 2, 34125, Trieste, Italy. m.biasotto@fmc.units.it.
University of Trieste · ITOspedale di Cattinara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucormycosis and aspergillosis are two opportunistic fungal infections, which can evolve into life-threatening complications. They generally affect patients with relevant risk factors such as immunocompromisation or long-term use of antibiotics or corticosteroids. Treatment usually combines medical and surgical approaches, often including extended necrosectomies, although the prognosis of generalized fungal infections is very poor. In this paper, we present the case of a 17-year-old girl affected by combined aspergillosis and mucormycosis, following treatment of a recurrent glioma. The patient was hospitalized for a suspected cellulitis of the right hemi-face, involving frontal maxillary area and the upper airways and was immediately put on intravenous antibiotic therapies; after performing nasal septum and maxillary biopsies, concomitant mucormycosis and aspergillosis were diagnosed and antimycotic therapy with liposomal B-amphotericin was administered. After evaluation by the oral surgeon and otolaryngologist, surgical cranio-facial necrosectomy was suggested, but refused by the parents of the patient. The girl died only few days later, due to a respiratory arrest. Awareness of this pathology with prompt diagnosis and early treatment may improve the outcome of these infections and reduce the mortality.

Indexed as

AdolescentAmphotericin BAntifungal AgentsAspergillosisBrainCoinfectionFacial DermatosesFatal OutcomeFemaleGliomaHistocytochemistryHumansMagnetic Resonance ImagingMaxillaMicroscopyMucormycosisAmphotericin BAntifungal Agentsliposomal amphotericin BAspergillosisEarly diagnosisInvasive fungal infectionMucormycosis

Identifiers

PMID27350324
OpenAlexW2465758282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.