ArticleeLife2016
Origins of the 2009 H1N1 influenza pandemic in swine in Mexico.
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 221 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
221 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Community Engagement Within the Evaluation of Public Policies for Zoonotic Spillover Prevention: A Secondary Matrix Analysis.International journal of environmental research and public health · 2025Pooled it
- Analysis of National Institutes of Health Funding for the COVID-19 Pandemic.Open forum infectious diseases · 2024Trial
- Phylodynamic reconstruction of H1N1pdm09 influenza virus transmission in Brazil: a decade of evolutionary dynamics.Emerging microbes & infections · 2026Article
- Substitutions affecting the HA-NA-receptor balance preceded the emergence of the pandemic 2009 H1N1 virus.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Genetic Variability and Evolutionary Dynamics of A(H1N1)pdm09 in Italy Before, During, and After the COVID-19 Pandemic.Pathogens (Basel, Switzerland) · 2026Article
- Occupationally Exposed and General Population Antibody Profiles to Influenza A Viruses Circulating in Swine as Indication of Zoonotic Risk.Emerging infectious diseases · 2026Article
- Genomic Characterization and Structural Insights Into the Evolution of Influenza A(H1N1)pdm09 in Northeast India From 2009 to 2024.Journal of medical virology · 2026Article
- Building resilient food safety systems through a One Health approach to prepare for the next pandemic.NPJ science of food · 2026Review
- Seabirds' mortalities in Antarctica caused by HPAIV: skuas as a sentinel species.Epidemiology and infection · 2026Article
- Human-Origin Influenza A(H3N2) Viruses Revealed in Swine Farms During the Period 2022-2025 in Kazakhstan.Animals : an open access journal from MDPI · 2026Article
- A Retrospective Cross-Sectional Study (2009-2023): Exploring Influenza A(H1N1)pdm09 Antibody Time Series in Humans and Swine and Vaccine Coverage in Two Target Groups.Zoonoses and public health · 2026Article
- A precision-cut lung slice platform for evaluating respiratory virus replication dynamics.bioRxiv : the preprint server for biology · 2026Article
- Historical Pandemic and Contemporary Influenza A Viruses Reveal PB2 M631L as a Convergent Adaptation to Human ANP32.Microorganisms · 2026Article
- Genetic diversity and circulation of influenza A viruses in Italian pig farms: insights from surveillance and vaccination.Porcine health management · 2026Article
- Identification of a Key Hemagglutinin Mutation Mediating Antibody Escape in Influenza A(H1N1)pdm09 Viruses.Viruses · 2026Article
- First report of human infection caused by swine-origin influenza A(H1N2)v virus in mainland China: a confirmed case identified through influenza-like illness surveillance, Kunming (Yunnan), 2025.Frontiers in public health · 2026Article
- Characterizing acute and persistent symptoms of COVID-19 among adults and children in rural Zambia, 2020-2022.PLOS global public health · 2026Article
- Learning from pandemics: Feature selection and clustering for robust digital disease nowcasting.PloS one · 2026Article
- The ribosomal landscape in influenza A virus infection: from molecular mechanisms to clinical relevance.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Influenza Surveillance in the Central African Republic From 2015 to 2018 to Inform Vaccination and Treatment Strategies.Influenza and other respiratory viruses · 2026Article
161 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Asia is considered an important source of influenza A virus (IAV) pandemics, owing to large, diverse viral reservoirs in poultry and swine. However, the zoonotic origins of the 2009 A/H1N1 influenza pandemic virus (pdmH1N1) remain unclear, due to conflicting evidence from swine and humans. There is strong evidence that the first human outbreak of pdmH1N1 occurred in Mexico in early 2009. However, no related swine viruses have been detected in Mexico or any part of the Americas, and to date the most closely related ancestor viruses were identified in Asian swine. Here, we use 58 new whole-genome sequences from IAVs collected in Mexican swine to establish that the swine virus responsible for the 2009 pandemic evolved in central Mexico. This finding highlights how the 2009 pandemic arose from a region not considered a pandemic risk, owing to an expansion of IAV diversity in swine resulting from long-distance live swine trade.
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