ArticleScientific reports2016
Heterologous expression of a rice miR395 gene in Nicotiana tabacum impairs sulfate homeostasis.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 58 citations in OpenAlex.
- Sulfur Homeostasis in Rice as a Dynamic Regulatory Network: Functional Genomics, Metabolic Crosstalk, and miR395-Mediated Control.Molecular biotechnology · 2026Review
- Functional Genomics of Sulfur Metabolism in Rice: Insights From Transgenic and MicroRNA-Based Strategies.Plant direct · 2026Review
- Ectopic expression of maize gene ZmDUF1645 in rice affects rice grain traits and cold tolerance.BMC plant biology · 2025Article
- MicroRNAs-mediated heat stress regulations in plants: Mechanisms and targets.The plant genome · 2025Review
- Non-coding RNAs in plant stress responses: molecular insights and agricultural applications.Plant biotechnology journal · 2025Review
- MicroRNA gatekeepers: Orchestrating rhizospheric dynamics.Journal of integrative plant biology · 2025Review
- The Roles of MicroRNAs in the Regulation of Rice-Pathogen Interactions.Plants (Basel, Switzerland) · 2025Review
- Review
- Noncoding RNAs and their roles in regulating the agronomic traits of crops.Fundamental research · 2023Review
- microRNA408 and its encoded peptide regulate sulfur assimilation and arsenic stress response in Arabidopsis.Plant physiology · 2023Article
- Editorial: Advances on genomics and genetics of horticultural crops and their contribution to breeding efforts.Frontiers in plant science · 2023Article
- Review
- microRNAs: Key Players in Plant Response to Metal Toxicity.International journal of molecular sciences · 2022Review
- Identification and Characterization of Csa-miR395s Reveal Their Involvements in Fruit Expansion and Abiotic Stresses in Cucumber.Frontiers in plant science · 2022Article
- MiR395c Regulates Secondary Xylem Development Through Sulfate Metabolism in Poplar.Frontiers in plant science · 2022Article
- Genome-wide small RNA profiling reveals tiller development in tall fescue (Festuca arundinacea Schreb).BMC genomics · 2020Article
- Dynamic architecture and regulatory implications of the miRNA network underlying the response to stress in melon.RNA biology · 2020Article
- Evolution of Disease Defense Genes and Their Regulators in Plants.International journal of molecular sciences · 2019Review
- Redox Balance-DDR-miRNA Triangle: Relevance in Genome Stability and Stress Responses in Plants.Frontiers in plant science · 2019Review
- Heterologous Expression ofInternational journal of molecular sciences · 2018Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sulfur participates in many important mechanisms and pathways of plant development. The most common source of sulfur in soil -SO4(2-)- is absorbed into root tissue and distributed into aerial part through vasculature system, where it is reduced into sulfite and finally sulfide within the subcellular organs such as chloroplasts and mitochondria and used for cysteine and methionine biosynthesis. MicroRNAs are involved in many regulation pathways by repressing the expression of their target genes. MiR395 family in Arabidopsis thaliana has been reported to be an important regulator involved in sulfate transport and assimilation, and a high-affinity sulphate transporter and three ATP sulfurylases (ATPS) were the target genes of AthmiR395 (Arabidopsis thaliana miR395). We have cloned a miR395 gene from rice (Oryza sativa) and studied its function in plant nutritional response. Our results indicated that in rice, transcript level of OsamiR395 (Oryza sativa miR395) increased under sulfate deficiency conditions, and the two predicted target genes of miR395 were down-regulated under the same conditions. Overexpression of OsamiR395h in tobacco impaired its sulfate homeostasis, and sulfate distribution was also slightly impacted among leaves of different ages. One sulfate transporter (SULTR) gene NtaSULTR2 was identified to be the target of miR395 in Nicotiana tobacum, which belongs to low affinity sulfate transporter group. Both miR395 and NtaSULTR2 respond to sulfate starvation in tobacco.
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