ReviewNeuroscience and biobehavioral reviews2018
Genetic influences on conduct disorder.
Review in Neuroscience and biobehavioral reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Epigenome-wide DNA methylation in externalizing behaviours: A review and combined analysis.Neuroscience and biobehavioral reviews · 2023Pooled it
- The methylome in females with adolescent Conduct Disorder: Neural pathomechanisms and environmental risk factors.PloS one · 2022Trial
- Gene-Environment Interplay Beyond Interactions: Psychosocial Environments Mediate Genetic Effects Underlying Externalizing-Behavior Trajectories.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Callous-Unemotional Traits and Their Association with Neurodevelopmental Disorders: Insights from Gaze Behaviour During Emotion Recognition.Children (Basel, Switzerland) · 2026Review
- Behavior choices amongst grooming, feeding and courting in Drosophila show contextual flexibility, not an absolute hierarchy of needs.The Journal of experimental biology · 2025Article
- Externalizing behaviors in children living near coal-fired power plants.BMC public health · 2025Article
- Environmental Risk Factors of Conduct Disorder: An Overview of Meta-Analyses.Iranian journal of psychiatry · 2025Review
- Investigation of Relationship with God among Adolescents with Conduct Disorder: A Qualitative Content Analysis.Iranian journal of psychiatry · 2025Article
- The power of parenting: mitigating conduct problems among adolescents carrying genetic risk.Frontiers in child and adolescent psychiatry · 2025Article
- Examining intergenerational risk factors for conduct problems using polygenic scores in the Norwegian Mother, Father and Child Cohort Study.Molecular psychiatry · 2024Article
- Exploring the interplay of dopaminergic genotype and parental behavior in relation to executive function in early childhood.Development and psychopathology · 2023Article
- Resting heart rate and antisocial behaviour: a Mendelian randomisation study.Scientific reports · 2023Article
- SLC25A24 gene methylation and gray matter volume in females with and without conduct disorder: an exploratory epigenetic neuroimaging study.Translational psychiatry · 2021Article
- Polygenic Risk for Aggression Predicts Adult Substance Use Disorder Diagnoses via Substance Use Offending in Emerging Adulthood and is Moderated by a Family-Centered Intervention.Behavior genetics · 2021Article
- Detention in Juvenile Correctional Facilities Is Associated with Higher Platelet Monoamine Oxidase B Activity in Males.Biomolecules · 2020Article
- Parenting and prenatal risk as moderators of genetic influences on conduct problems during middle childhood.Developmental psychology · 2019Article
- Psychiatric Genetics, Epigenetics, and Cellular Models in Coming Years.Journal of psychiatry and brain science · 2019Article
- Cultures and Persons: Characterizing National and Other Types of Cultural Difference Can Also Aid Our Understanding and Prediction of Individual Variability.Frontiers in psychology · 2019Review
- Biological explanations of criminal behavior.Psychology, crime & law : PC & L · 2019Article
- Violence exposure in an urban city: A GxE interaction with aggressive and impulsive behaviors.Journal of child psychology and psychiatry, and allied disciplines · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Conduct disorder (CD) is a moderately heritable psychiatric disorder of childhood and adolescence characterized by aggression toward people and animals, destruction of property, deceitfulness or theft, and serious violation of rules. Genome-wide scans using linkage and association methods have identified a number of suggestive genomic regions that are pending replication. A small number of candidate genes (e.g., GABRA2, MAOA, SLC6A4, AVPR1A) are associated with CD related phenotypes across independent studies; however, failures to replicate also exist. Studies of gene-environment interplay show that CD genetic predispositions also contribute to selection into higher-risk environments, and that environmental factors can alter the importance of CD genetic factors and differentially methylate CD candidate genes. The field's understanding of CD etiology will benefit from larger, adequately powered studies in gene identification efforts; the incorporation of polygenic approaches in gene-environment interplay studies; attention to the mechanisms of risk from genes to brain to behavior; and the use of genetically informative data to test quasi-causal hypotheses about purported risk factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.