Evidence map›Paper›PMID 27349836›Full record

ArticleScientific reports2016

Sol-gel synthesis of thorn-like ZnO nanoparticles endorsing mechanical stirring effect and their antimicrobial activities: Potential role as nano-antibiotics.

Mohd Farhan Khan, Akhter H Ansari, M Hameedullah, Ejaz Ahmad, Fohad Mabood Husain, Qamar Zia, Umair Baig, Mohd Rehan Zaheer, Mohammad Mezbaul Alam, Abu Mustafa Khan and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Green Synthesis of ZnO Nanoparticles UsingNanomaterials (Basel, Switzerland) · 2026
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mohd Farhan KhanNano Solver Lab, Department of Mechanical Engineering, Z. H. College of Engineering &Technology, Aligarh Muslim University, Aligarh-202002, India.
Akhter H AnsariNano Solver Lab, Department of Mechanical Engineering, Z. H. College of Engineering &Technology, Aligarh Muslim University, Aligarh-202002, India.
M HameedullahNano Solver Lab, Department of Mechanical Engineering, Z. H. College of Engineering &Technology, Aligarh Muslim University, Aligarh-202002, India.
Ejaz AhmadDepartment of Biological Sciences, University of Toledo, Toledo, OH43606, USA.
Fohad Mabood HusainDepartment of Agricultural Microbiology, Aligarh Muslim University, Aligarh-202002, India.
Qamar ZiaInterdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh-202002, India.
Umair BaigCenter of Excellence for Scientific Research Collaboration with MIT, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia.
Mohd Rehan ZaheerFaculty of Science, Gagan College of Management &Technology (GCMT), Aligarh-202002, India.
Mohammad Mezbaul AlamAdvanced Materials Research Chair, Chemistry Department, College of Sciences, Building 5, King Saud University, Riyadh-11451, Kingdom of Saudi Arabia.
Abu Mustafa KhanDepartment of Chemistry, Aligarh Muslim University, Aligarh-202002, India.
Zeid A AlOthmanAdvanced Materials Research Chair, Chemistry Department, College of Sciences, Building 5, King Saud University, Riyadh-11451, Kingdom of Saudi Arabia.
Iqbal AhmadDepartment of Agricultural Microbiology, Aligarh Muslim University, Aligarh-202002, India.
Ghulam Md AshrafKing Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.
Gjumrakch AlievGALLY International Biomedical Research Consulting LLC., 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of mechanical stirring on sol-gel synthesis of thorn-like ZnO nanoparticles (ZnO-NPs) and antimicrobial activities is successfully reported in this study. The in-house synthesized nanoparticles were characterized by XRD, SEM, TEM, FTIR, TGA, DSC and UV-visible spectroscopy. The X-Ray Diffraction analysis revealed the wurtzite crystal lattice for ZnO-NPs with no impurities present. The diametric measurements of the synthesized thorn-like ZnO-NPs (morphology assessed by SEM) were well accounted to be less than 50 nm with the help of TEM. Relative decrease in aspect ratio was observed on increasing the agitation speed. The UV-visible spectroscopy showed the absorption peaks of the ZnO-NPs existed in both UVA and UVB region. A hypsochromic shift in λmax was observed when stirring pace was increased from 500 rpm to 2000 rpm. The FTIR spectroscopy showed the absorption bands of the stretching modes of Zn-O between 500 cm(-1) to 525 cm(-1). The Thermal analysis studies revealed better stability for ZnO-NPs prepared at 2000 rpm (ZnO-2000 rpm). TGA revealed the weight loss between two main temperatures ranges viz. around (90 °C-120 °C) and (240 °C-280 °C). Finally, the effect of ZnO-NPs prepared at different stirring conditions on the growth of Gram-positive (Bacillus subtilis), Gram-negative (Escherichia coli) bacteria and a fungi (Candida albicans) were examined; which showed good antibacterial as well as antifungal properties. These findings introduce a simple, inexpensive process to synthesize ZnO-NPs using conventional methods without the use of sophisticated equipments and its application as a potent nano-antibiotic.

Indexed as

Phase TransitionAnti-Infective AgentsBacillus subtilisCalorimetry, Differential ScanningCandida albicansEscherichia coliHot TemperatureHumansMetal NanoparticlesMicrobial Sensitivity TestsMicroscopy, Electron, ScanningMicroscopy, Electron, TransmissionSpectrophotometry, UltravioletSpectroscopy, Fourier Transform InfraredStress, MechanicalThermogravimetryAnti-Infective AgentsZinc Oxide

Identifiers

PMID27349836
PMCPMC4923881

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.