Evidence map›Paper›PMID 27349800›Full record

ArticleJournal of fluorescence2016

Sensitive Naked Eye and Autofluorescence Detection of Cu(2+) in Biological Fluids by Polyethyleneimine Microspheres.

Dan Yan, Chun Deng, Yu He, Yili Ge, Gongwu Song

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dan YanMinistry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, College of Chemistry and Chemical Engineering, Hubei University, Wuhan, 430062, China.
Chun DengMinistry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, College of Chemistry and Chemical Engineering, Hubei University, Wuhan, 430062, China.
Yu HeMinistry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, College of Chemistry and Chemical Engineering, Hubei University, Wuhan, 430062, China. heyu@hubu.edu.cn.ORCID http://orcid.org/0000-0002-8068-5825
Yili GeMinistry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, College of Chemistry and Chemical Engineering, Hubei University, Wuhan, 430062, China.
Gongwu SongMinistry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, College of Chemistry and Chemical Engineering, Hubei University, Wuhan, 430062, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, an autofluorencent polyethyleneimine (PEI) microspheres probe has been designed as the two channel sensor for both quantitative fluorescence and visual detection of Cu(2+). We synthesized autofluorescent microspheres crosslinked with glutaraldehyde by controlling volume ratio between oil phase and water phase. A novel fluorescent platform for sensing Cu(2+) based on the autofluorescence quenching of PEI microspheres by Cu(2+) with a detection limit as low as 2 nM. In addition, the absorbance of PEI microspheres at 205 nm, 325 nm, 590 nm and 800 nm were sensitive to the presence of Cu(2+). The strong chelation interaction between Cu(2+) and -NH2 on the surface of microspheres produced the fluorescence quenching and color change of PEI microspheres which facilitated our sensing approach. We regard the developing of autofluorcent PEI microspheres as the dual-channel sensor for Cu(2+) would provide autofluorcent microspheres a future application in quantitative analysis.

Indexed as

FluorescenceMicrospheresCopperFluorescent DyesHumansMetal NanoparticlesPolyethyleneimineSpectrometry, FluorescenceWaterCopperFluorescent DyesPolyethyleneimineWaterAutofluorescent microspheresCu2+Fluorescence quenchingVisual detection

Identifiers

PMID27349800

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.