Evidence map›Paper›PMID 27349656›Full record

ArticleChild psychiatry and human development2017

Depression with Mixed Features in Adolescent Psychiatric Patients.

Elisabeth A Frazier, Lance P Swenson, Tracy Mullare, Daniel P Dickstein, Jeffrey I Hunt

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Child psychiatry and human development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elisabeth A FrazierDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA. elisabeth_frazier@brown.edu.ORCID 0000-0001-5995-8465
Lance P SwensonDepartment of Psychology, Suffolk University, Boston, MA, USA.
Tracy MullareDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.
Daniel P DicksteinDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.
Jeffrey I HuntDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression with mixed features is poorly understood, especially in pediatric samples. This study compares symptoms and correlates of depressed adolescent inpatients with mixed features to inpatients with bipolar disorder and major depression. 407 adolescents were administered diagnostic interviews and self-reports, and 262 were categorized as Depression with Mixed Features (MXD; n = 38), Consensus Bipolar (CB; n = 79), or Depression Only (DO; n = 145). Demographic and morbidity information were collected via chart reviews. MXD adolescents evidenced elevated mania-related symptoms compared to DO adolescents. MXD adolescents had elevated Unusually Energetic symptoms and increases for six additional category B mania-related symptoms compared to CB adolescents. MXD adolescents met criteria for more comorbid disorders and reported elevated suicidality, anger, and trauma symptoms compared to CB and DO adolescents. Overall, MXD adolescents evidenced elevated symptomatology compared to other groups, suggesting mixed depression may represent a unique constellation of symptoms meriting further investigation.

Indexed as

Bipolar DisorderDepressionMajor Depressive DisorderAdolescentComorbidityDemographyDiagnosis, DifferentialFemaleHumansInpatientsMaleSelf ReportSymptom AssessmentAdolescent inpatientsDepression with mixed featuresMood disorders

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.