Evidence map›Paper›PMID 27349602›Full record

ArticleParkinsonism & related disorders2016

Juvenile onset Parkinsonism with "pure nigral" degeneration and POLG1 mutation.

Shyamal H Mehta, Dennis W Dickson, John C Morgan, Andrew B Singleton, Elisa Majounie, Kapil D Sethi

Abstract readLetter
In one paragraph

Article in Parkinsonism & related disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Rethinking Mitochondrial Parkinson's Disease in the α-Synuclein Seed Amplification Assays Era.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  2. Multi-ancestry analysis ofmedRxiv : the preprint server for health sciences · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Neuropathology of Parkinson disease.Parkinsonism & related disorders · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shyamal H MehtaDepartment of Neurology, Mayo Clinic, Scottsdale, AZ 85259, USA. Electronic address: mehta.shyamal@mayo.edu.
Dennis W DicksonDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
John C MorganDepartment of Neurology, Medical College of Georgia, Augusta, GA 30912, USA.
Andrew B SingletonMolecular Genetics Section, National Institute on Aging, Bethesda, MD 20892, USA.
Elisa MajounieMolecular Genetics Section, National Institute on Aging, Bethesda, MD 20892, USA.
Kapil D SethiDepartment of Neurology, Medical College of Georgia, Augusta, GA 30912, USA.

Funding

Vascular Structure and Function in Cognitive AgingP01AG003949 · NIA · YESHIVA UNIVERSITY · PI Richard B. LIPTON · 1985 to 2026
$73.9M
THE PGRN/TDP-43 AXIS IN ALZHEIMER?S DISEASE AND NEURODEGENERATIONP50AG016574 · NIA · MAYO CLINIC ROCHESTER · PI BU, GUOJUN · 1999 to 2018
$36.9M
Project 3: Neuropathology of the multi-proteinopathy of c9FTD/ALS.P01NS084974 · NINDS · MAYO CLINIC JACKSONVILLE · PI PETRUCELLI, LEONARD · 2014 to 2024
$17.6M
Genome wide SNP analysis in Parkinson's diseaseZIAAG000949 · NIA · NATIONAL INSTITUTE ON AGING · PI SINGLETON, ANDREW · 2009 to 2024
$12.6M
Genetic analysis in families with neurological diseaseZIAAG000958 · NIA · NATIONAL INSTITUTE ON AGING · PI SINGLETON, ANDREW · 2009 to 2024
$10.9M
Neuropathology CoreP50NS072187 · NINDS · MAYO CLINIC JACKSONVILLE · PI DICKSON, DENNIS WILLIAM · 2010 to 2017
$8.7M
Genome wide SNP analysis in Parkinson's diseaseZ01AG000949 · NIA · NATIONAL INSTITUTE ON AGING · PI SINGLETON, ANDREW B · 2006 to 2008
$2.6M
Intramural NIH HHS Z01 AG000949Intramural NIH HHS Z99 AG999999NIA NIH HHS P01 AG003949NIA NIH HHS P50 AG016574NINDS NIH HHS P01 NS084974NINDS NIH HHS P50 NS072187
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAge of OnsetDNA Polymerase gammaFemaleHumansMaleMutationParkinsonian DisordersSiblingsSubstantia NigraYoung AdultDNA Polymerase gammaPOLG protein, human

Identifiers

PMID27349602
PMCPMC5995126

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.