Evidence map›Paper›PMID 27349461›Full record

ArticleOsteoarthritis and cartilage2017

Mindfulness is associated with psychological health and moderates pain in knee osteoarthritis.

A C Lee, W F Harvey, L L Price, L P K Morgan, N L Morgan, C Wang

Registry-linked trialAbstract read
In one paragraph

Article in Osteoarthritis and cartilage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03936088 (Use of a Self-Guided Mindfulness Mobile Application to Improve Pain Outcomes in Individuals With Knee Osteoarthritis), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03936088 nacompletednot on this mapstarted 2019, after this paper: background citation

Use of a Self-Guided Mindfulness Mobile Application to Improve Pain Outcomes in Individuals With Knee Osteoarthritis

TypeinterventionalSponsorjilliansylvesterRan2019 to 2022Enrolled75ConditionsOsteo Arthritis Knee, PainArmsIntervention -- "Headspace" mindfulness application, Control -- "My Water Balance" application
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

A C LeeCenter for Complementary and Integrative Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA, USA. Electronic address: Alee10@Tuftsmedicalcenter.org.
W F HarveyCenter for Complementary and Integrative Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA, USA. Electronic address: WHarvey@Tuftsmedicalcenter.org.
L L PriceInstitute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, USA; Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, USA. Electronic address: Lprice1@Tuftsmedicalcenter.org.
L P K MorganDepartment of Psychology, University of Massachusetts Boston, Boston, MA, USA; I Ola Lahui Rural Hawai'i Behavioral Health, Honolulu, HI, USA. Electronic address: lucas.morgan@gmail.com.
N L MorganCenter for Complementary and Integrative Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA, USA; Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA. Electronic address: nani.loui@gmail.com.
C WangCenter for Complementary and Integrative Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA, USA. Electronic address: CWang2@Tuftsmedicalcenter.org.
Tufts Medical Center · USHawaii Department of Health · USTufts University · USUniversity of Hawaiʻi at Mānoa · US

Funding

Tufts Clinical and Translational Research InstituteUL1TR001064 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2013 to 2017
$26.4M
Tai Chi for Knee OsteoarthritisR01AT005521 · NCCIH · TUFTS MEDICAL CENTER · PI WANG, CHENCHEN · 2010 to 2013
$2.4M
Mentoring and Research in Patient-Oriented Integrative MedicineK24AT007323 · NCCIH · TUFTS MEDICAL CENTER · PI WANG, CHENCHEN · 2014 to 2023
$1.8M
NCATS NIH HHS UL1 TR001064NCCIH NIH HHS K24 AT007323NCCIH NIH HHS R01 AT005521
6 · The paper itself

Abstract

objectivePrevious studies suggest that higher mindfulness is associated with less pain and depression. However, the role of mindfulness has never been studied in knee osteoarthritis (OA). We evaluate the relationships between mindfulness and pain, psychological symptoms, and quality of life in knee OA.

methodWe performed a secondary analysis of baseline data from our randomized comparative trial in participants with knee OA. Mindfulness was assessed using the Five Facet Mindfulness Questionnaire (FFMQ). We measured pain, physical function, quality of life, depression, stress, and self-efficacy with commonly-used patient-reported measures. Simple and multivariable regression models were utilized to assess associations between mindfulness and health outcomes. We further tested whether mindfulness moderated the pain-psychological outcome associations.

resultsEighty patients were enrolled (60.3 ± 10.3 years; 76.3% female, body mass index: 33.0 ± 7.1 kg/m

conclusionMindfulness is associated with depression, stress, self-efficacy, and quality of life among knee OA patients. Mindfulness also moderates the influence of pain on stress, which suggests that mindfulness may alter the way one copes with pain. Future studies examining the benefits of mind-body therapy, designed to increase mindfulness, for patients with OA are warranted.

Indexed as

Mental HealthMindfulnessSelf EfficacyAgedArthralgiaCross-Sectional StudiesDepressionFemaleHumansMaleMiddle AgedOsteoarthritis, KneePatient Reported Outcome MeasuresQuality of LifeRandomized Controlled Trials as TopicStress, PsychologicalChronic painMindfulnessOsteoarthritisPsychological stress

Identifiers

PMID27349461
PMCPMC5183521
OpenAlexW2460926952

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.