ArticleEBioMedicine2016
Pons to Posterior Cingulate Functional Projections Predict Affective Processing Changes in the Elderly Following Eight Weeks of Meditation Training.
Article in EBioMedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Meta-analytic evidence that mindfulness training alters resting state default mode network connectivity.Scientific reports · 2022Pooled it
- Trial
- Trial
- Decoding Depth of Meditation: Electroencephalography Insights From Expert Vipassana Practitioners.Biological psychiatry global open science · 2025Article
- Article
- Neuroimaging evaluation of the long term impact of a novel paired meditation practice on brain function.Frontiers in neuroimaging · 2024Article
- Three potential neurovascular pathways driving the benefits of mindfulness meditation for older adults.Frontiers in aging neuroscience · 2023Review
- Sensory processing sensitivity and axonal microarchitecture: identifying brain structural characteristics for behavior.Brain structure & function · 2022Article
- Asymmetric affective perspective taking effects toward valence influenced by personality perspective taken.Psychonomic bulletin & review · 2022Article
- Amygdala-pons connectivity is hyperactive and associated with symptom severity in depression.Communications biology · 2022Article
- Alterations in Brain Structure and Amplitude of Low-frequency after 8 weeks of Mindfulness Meditation Training in Meditation-Naïve Subjects.Scientific reports · 2019Article
- Default Mode Network, Meditation, and Age-Associated Brain Changes: What Can We Learn from the Impact of Mental Training on Well-Being as a Psychotherapeutic Approach?Neural plasticity · 2019Review
- Tai Chi Improves Brain Metabolism and Muscle Energetics in Older Adults.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2018Article
- A longitudinal study of the effect of short-term meditation training on functional network organization of the aging brain.Scientific reports · 2017Article
- Moderating Effects of Cortisol on Neural-Cognitive Association in Cognitively Normal Elderly Subjects.Frontiers in aging neuroscience · 2017Article
- "Just This Breath…" How Mindfulness Meditation Can Shift Everything, Including Neural Connectivity.EBioMedicine · 2016Article
- Meditation-induced neuroplastic changes of the prefrontal network are associated with reduced valence perception in older people.Brain and neuroscience advancesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evidence indicates meditation facilitates affective regulation and reduces negative affect. It also influences resting-state functional connectivity between affective networks and the posterior cingulate (PCC)/precuneus, regions critically implicated in self-referential processing. However, no longitudinal study employing active control group has examined the effect of meditation training on affective processing, PCC/precuneus connectivity, and their association. Here, we report that eight-week meditation, but not relaxation, training 'neutralized' affective processing of positive and negative stimuli in healthy elderly participants. Additionally, meditation versus relaxation training increased the positive connectivity between the PCC/precuneus and the pons, the direction of which was largely directed from the pons to the PCC/precuneus, as revealed by dynamic causal modeling. Further, changes in connectivity between the PCC/precuneus and pons predicted changes in affective processing after meditation training. These findings indicate meditation promotes self-referential affective regulation based on increased regulatory influence of the pons on PCC/precuneus, which new affective-processing strategy is employed across both resting state and when evaluating affective stimuli. Such insights have clinical implications on interventions on elderly individuals with affective disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.