ArticleNature communications2016
Enhancing digestibility and ethanol yield of Populus wood via expression of an engineered monolignol 4-O-methyltransferase.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 85 citations in OpenAlex.
- A Dual-gRNA CRISPR/Cas9 System for Efficient Generation of Large Fragment Deletions in Poplar.Bio-protocol · 2026Article
- From Defense Executor to Engineering Target: Harnessing Lignin for Crop Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Enhanced saccharification yields from rice straw by senescence-induced expression of a cytokinin biosynthesis gene in intragenic rice plants.Plant biotechnology (Tokyo, Japan) · 2026Article
- Engineering 2-Pyrone-4,6-Dicarboxylic Acid Production Reveals Metabolic Plasticity of Poplar.Plant biotechnology journal · 2026Article
- Boosting lignocellulosic bioethanol production: fermentation of corn stalk using a lignin-reduced brown midrib 2 maize mutant.Biotechnology for biofuels and bioproducts · 2025Article
- Comprehensive analysis of the Caffeic acid O-methyltransferase gene family in kenaf (Frontiers in plant science · 2025Article
- Article
- Knockout of ZmNST2 promotes bioethanol production from corn stover.Plant biotechnology journal · 2024Article
- Synthetic-biology approach for plant lignocellulose engineering.Plant biotechnology (Tokyo, Japan) · 2024Article
- Simultaneous suppression of lignin, tricin and wall-bound phenolic biosynthesis via the expression of monolignol 4-O-methyltransferases in rice.Plant biotechnology journal · 2024Article
- Genome-wide characterization of COMT family and regulatory role of CsCOMT19 in melatonin synthesis in Camellia sinensis.BMC plant biology · 2024Article
- A comprehensive review on genetic modification of plant cell wall for improved saccharification efficiency.Molecular biology reports · 2023Review
- Lignin engineering in forest trees: From gene discovery to field trials.Plant communications · 2022Review
- Identification and Functional Analysis of the Caffeic Acid O-Methyltransferase (COMT) Gene Family in Rice (International journal of molecular sciences · 2022Article
- Scanning structural mapping at the Life Science X-ray Scattering Beamline.Journal of synchrotron radiation · 2022Article
- Carbohydrate-aromatic interface and molecular architecture of lignocellulose.Nature communications · 2022Article
- Monolignol acyltransferase for lignin p-hydroxybenzoylation in Populus.Nature plants · 2021Article
- Overexpression of vesicle-associated membrane protein PttVAP27-17 as a tool to improve biomass production and the overall saccharification yields in Populus trees.Biotechnology for biofuels · 2021Article
- Genome-wide identification and characterization of COMT gene family during the development of blueberry fruit.BMC plant biology · 2021Article
- LACCASE14 is required for the deposition of guaiacyl lignin and affects cell wall digestibility in poplar.Biotechnology for biofuels · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Producing cellulosic biofuels and bio-based chemicals from woody biomass is impeded by the presence of lignin polymer in the plant cell wall. Manipulating the monolignol biosynthetic pathway offers a promising approach to improved processability, but often impairs plant growth and development. Here, we show that expressing an engineered 4-O-methyltransferase that chemically modifies the phenolic moiety of lignin monomeric precursors, thus preventing their incorporation into the lignin polymer, substantially alters hybrid aspens' lignin content and structure. Woody biomass derived from the transgenic aspens shows a 62% increase in the release of simple sugars and up to a 49% increase in the yield of ethanol when the woody biomass is subjected to enzymatic digestion and yeast-mediated fermentation. Moreover, the cell wall structural changes do not affect growth and biomass production of the trees. Our study provides a useful strategy for tailoring woody biomass for bio-based applications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.