Beta-blockers in septic shock to optimize hemodynamics? No.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. The association between premorbid beta blocker exposure and mortality in sepsis-a systematic review.Critical care (London, England) · 2019
   Pooled it
2. Propafenone versus amiodarone for supraventricular arrhythmias in septic shock: a randomised controlled trial.Intensive care medicine · 2023
   Trial
3. Impact of heart rate on Doppler echocardiography predictors of rhythm control in patients with septic shock.Scientific reports · 2026
   Article
4. Effect of premorbid beta-blockers on cardiac function and clinical outcomes in septic patients: a retrospective study.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2026
   Article
5. Septic Cardiomyopathy: Difficult Definition, Challenging Diagnosis, Unclear Treatment.Journal of clinical medicine · 2025
   Review
6. Evaluation of Amiodarone Administration in Patients with New-Onset Atrial Fibrillation in Septic Shock.Medicina (Kaunas, Lithuania) · 2024
   Review
7. The influence of metoprolol in patients with sepsis-induced cardiomyopathy: A retrospective study.Saudi medical journal · 2023
   Article
8. Ventriculo-arterial (un)coupling in septic shock: Impact of current and upcoming hemodynamic drugs.Frontiers in cardiovascular medicine · 2023
   Review
9. Septic cardiomyopathy: Diagnosis and management.Journal of intensive medicine · 2022
   Review
10. Reliability of effective arterial elastance using peripheral arterial pressure as surrogate for left ventricular end-systolic pressure.Journal of clinical monitoring and computing · 2019
    Article
11. Efficacy and safety of 1C class antiarrhythmic agent (propafenone) for supraventricular arrhythmias in septic shock compared to amiodarone: protocol of a prospective randomised double-blind study.BMJ open · 2019
    Article

Corrections and comments

• Comment on
  Heart rate reduction with esmolol is associated with improved arterial elastance in patients with septic shock: a prospective observational study.2016

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as