ArticlePloS one2016
Regional Longitudinal Myocardial Deformation Provides Incremental Prognostic Information in Patients with ST-Segment Elevation Myocardial Infarction.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Anterior STEMI associated with decreased strain in remote cardiac myocardium.The international journal of cardiovascular imaging · 2022Trial
- Left ventricular deformation predicts major adverse cardiac events following acute myocardial infarction independently of afterload and ventricular-arterial coupling.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Ratio of early transmitral inflow velocity to early diastolic strain rate predicts atrial fibrillation following acute myocardial infarction.The international journal of cardiovascular imaging · 2024Article
- Association between left ventricular systolic function parameters and myocardial injury, organ failure and mortality in patients with septic shock.Annals of intensive care · 2024Article
- Strain Imaging and Ventricular Arrhythmia.Diagnostics (Basel, Switzerland) · 2023Review
- Risk stratification in patients with hypertrophic cardiomyopathy: Looking beyond the left side myocardial function.Journal of the Chinese Medical Association : JCMA · 2023Article
- Severe Impairment of Left Ventricular Regional Strain in STEMI Patients Is Associated with Post-Infarct Remodeling.Journal of clinical medicine · 2022Article
- Subclinical dysfunction of remote myocardium is related to high NT-proBNP and affects global contractility at follow-up, independently of infarct area.Frontiers in cardiovascular medicine · 2022Article
- Layer-specific global longitudinal strain obtained by speckle tracking echocardiography for predicting heart failure and cardiovascular death following STEMI treated with primary PCI.The international journal of cardiovascular imaging · 2021Article
- Defining the optimal temporal and spatial resolution for cardiovascular magnetic resonance imaging feature tracking.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021Article
- Article
- Association between regional longitudinal strain and left ventricular thrombus formation following acute myocardial infarction.The international journal of cardiovascular imaging · 2020Article
- Early Systolic Lengthening in Patients With ST-Segment-Elevation Myocardial Infarction: A Novel Predictor of Cardiovascular Events.Journal of the American Heart Association · 2020Article
- Regional Left Ventricular Myocardial Dysfunction After Cardiac Surgery Characterized by 3-Dimensional Strain.Anesthesia and analgesia · 2019Article
- Cardiovascular magnetic resonance imaging feature tracking: Impact of training on observer performance and reproducibility.PloS one · 2019Article
- Prognostic importance of mechanical dyssynchrony in predicting heart failure development after ST-segment elevation myocardial infarction.The international journal of cardiovascular imaging · 2019Article
- Presence of post-systolic shortening is an independent predictor of heart failure in patients following ST-segment elevation myocardial infarction.The international journal of cardiovascular imaging · 2018Observational
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8 authors.
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Abstract
backgroundGlobal longitudinal systolic strain (GLS) has recently been demonstrated to be a superior prognosticator to conventional echocardiographic measures in patients after myocardial infarction (MI). The aim of this study was to evaluate the prognostic value of regional longitudinal myocardial deformation in comparison to GLS, conventional echocardiography and clinical information.
methodIn total 391 patients were admitted with ST-Segment elevation myocardial infarction (STEMI), treated with primary percutaneous coronary intervention and subsequently examined by echocardiography. All patients were examined by tissue Doppler imaging (TDI) and two-dimensional strain echocardiography (2DSE).
resultsDuring a median-follow-up of 5.3 (IQR 2.5-6.1) years the primary endpoint (death, heart failure or a new MI) was reached by 145 (38.9%) patients. After adjustment for significant confounders (including conventional echocardiographic parameters) and culprit lesion, reduced longitudinal performance in the anterior septal and inferior myocardial regions (but not GLS) remained independent predictors of the combined outcome. Furthermore, inferior myocardial longitudinal deformation provided incremental prognostic information to clinical and conventional echocardiographic information (Harrell's c-statistics: 0.63 vs. 0.67, p = 0.032). In addition, impaired longitudinal deformation outside the culprit lesion perfusion region was significantly associated with an adverse outcome (p<0.05 for all deformation parameters).
conclusionRegional longitudinal myocardial deformation measures, regardless if determined by TDI or 2DSE, are superior prognosticators to GLS. In addition, impaired longitudinal deformation in the inferior myocardial segment provides prognostic information over and above clinical and conventional echocardiographic risk factors. Furthermore, impaired longitudinal deformation outside the culprit lesion perfusion region seems to be a paramount marker of adverse outcome.
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