ArticleJournal of clinical medicine2016
The Impact of Remote Ischemic Preconditioning on Arterial Stiffness and Heart Rate Variability in Patients with Angina Pectoris.
Article in Journal of clinical medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Short-term effects of remote ischemic conditioning on vascular function in patients with cardiovascular diseases: a systematic review with meta-analysis.Einstein (Sao Paulo, Brazil) · 2025Pooled it
- Changes in cardiovascular health following ischemic preconditioning in older adults with knee osteoarthritis.Physiological reports · 2025Trial
- Acute effects of ischemic preconditioning and isometric exercise on blood pressure in prehypertensive males.Journal of exercise science and fitness · 2025Article
- Article
- Impact of ischemic preconditioning combined with aerobic exercise on 24-h ambulatory blood pressure in men with prehypertension and stage 1 hypertension.Frontiers in physiology · 2024Article
- A Single Bout of Remote Ischemic Preconditioning Suppresses Ischemia-Reperfusion Injury in Asian Obese Young Men.International journal of environmental research and public health · 2023Article
- Article
- Remote ischaemic preconditioning - translating cardiovascular benefits to humans.The Journal of physiology · 2022Review
- Remote ischemic preconditioning enhances aerobic performance by accelerating regional oxygenation and improving cardiac function during acute hypobaric hypoxia exposure.Frontiers in physiology · 2022Article
- Chronic Limb Remote Ischemic Conditioning may have an Antihypertensive Effect in Patients with Hypertension.Aging and disease · 2021Review
- The effect of remote ischaemic conditioning on blood pressure response: A systematic review and meta-analysis.International Journal of Cardiology. Hypertension · 2021Review
- Effects of Remote Ischemic Conditioning on Hand Engagement in individuals with Spinal cord Injury (RICHES): protocol for a pilot crossover study.F1000Research · 2021Article
- Effects of ischaemic conditioning on tissue oxygen saturation and heart rate variability: an observational study.The Journal of international medical research · 2019Observational
- Ischemic preconditioning boosts post-exercise but not resting cardiac vagal control in endurance runners.European journal of applied physiology · 2019Article
- Remote Ischemic Preconditioning Has No Short Term Effect on Blood Pressure, Heart Rate, and Arterial Stiffness in Healthy Young Adults.Frontiers in physiology · 2019Article
- Remote ischemic preconditioning triggers changes in autonomic nervous system activity: implications for cardioprotection.Physiological reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Remote ischemic preconditioning (RIPC) is the set of ischemia episodes that protects against subsequent periods of prolonged ischemia through the cascade of adaptive responses; however, the mechanisms of RIPC are not entirely clear. Here, we aimed to study the impact of RIPC in patients with stable angina pectoris and compare it with healthy individuals with respect to arterial stiffness and heart rate variability. In the randomized, sham-controlled, crossover blind design study, a group of 30 coronary heart disease (CHD) patients (63.9 ± 1.6 years) with stable angina pectoris NYHA II-III and a control group of 20 healthy individuals (58.2 ± 2.49) were both randomly allocated for remote RIPC or sham RIPC. Arterial stiffness, pulse wave velocity (Spygmacor, Australia), and heart rate variability (HRV) were recorded before and after the procedure followed by the crossover examination. In the group of healthy individuals, RIPC showed virtually no impact on the cardiovascular parameters, while, in the CHD group, the systolic and central systolic blood pressure, central pulse pressure, and augmentation decreased, and total power of HRV improved. We conclude that ischemic preconditioning reduces not only systolic blood pressure, but also reduces central systolic blood pressure and improves arterial compliance and heart rate modulation reserve, which may be associated with the antianginal effect of preconditioning.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.