Evidence map›Paper›PMID 27347995›Full record

ArticleNutrients2016

The Erythrocyte Fatty Acid Profile and Cognitive Function in Old Chinese Adults.

Linhong Yuan, Jie Zhen, Weiwei Ma, Can Cai, Xiaochen Huang, Rong Xiao

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Linhong YuanSchool of Public Health, Capital Medical University, Beijing 100069, China. ylhmedu@126.com.
Jie ZhenSchool of Public Health, Capital Medical University, Beijing 100069, China. xiaorong22@ccmu.edu.cn.
Weiwei MaSchool of Public Health, Capital Medical University, Beijing 100069, China. weiweizibeike@163.com.
Can CaiSchool of Public Health, Capital Medical University, Beijing 100069, China. ccfdzz1023@163.com.
Xiaochen HuangSchool of Public Health, Capital Medical University, Beijing 100069, China. xiaochenhuang@126.com.
Rong XiaoSchool of Public Health, Capital Medical University, Beijing 100069, China. Xiaor22@ccmu.edu.cn.
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the relationship between the erythrocyte fatty acid profile and cognition in elderly Chinese adults.

methods60 mild cognitive impairment (MCI) subjects and 60 age- and gender-matched control adults (aged 55 years and above) were involved in this cross-sectional study. Cognitive function was measured by using the Montreal Cognitive Assessment (MoCA) test. Information regarding the demographic characteristics and lifestyle of the participants was collected with a questionnaire. A semi-quantified food frequency questionnaire (FFQ) method was used for dietary assessment. The erythrocytes fatty acid profile was measured.

resultsThe MCI subjects had a lower education level than the control subjects (p < 0.05). Compared with control subjects, MCI subjects had higher daily poultry intake and lower fish intake (p < 0.05). Erythrocyte fatty acid profile of the MCI subjects was characterized as lower erythrocyte proportions of 20:4 n-6, 20:5 n-3, and total n-3 fatty acids compared with control subjects (p < 0.05). An association of erythrocyte proportions of 18:0, 22:0, total SFA, 18:2 n-6, 24:4 n-6 fatty acids, docosahexaenoic acid (DHA), and total n-6 PUFAs with cognition in elderly Chinese adults was detected.

conclusionThe erythrocyte fatty acid profile was related to cognitionin the elderly. Lower erythrocyte unsaturated fatty acid and higher saturated fatty acid proportions might predict cognitive function decline in elderly Chinese adults.

Indexed as

Asian PeopleAgedBlood GlucoseBody Mass IndexCholesterol, HDLCholesterol, LDLCognitionCognitive DysfunctionCross-Sectional StudiesDocosahexaenoic AcidsEicosapentaenoic AcidEnergy IntakeErythrocytesFatty AcidsFatty Acids, Omega-6FemaleBlood GlucoseCholesterol, HDLCholesterol, LDLDocosahexaenoic AcidsEicosapentaenoic AcidFatty AcidsFatty Acids, Omega-6Triglyceridescognitionerythrocyte fatty acidslipidsthe elderly

Identifiers

PMID27347995
PMCPMC4963861
OpenAlexW2466030311

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.