Evidence map›Paper›PMID 27347559›Full record

ArticleACS biomaterials science & engineering2016

Biodegradable Elastomers with Antioxidant and Retinoid-like Properties.

Robert van Lith, Xuesong Wang, Guillermo Ameer

Open access · greenAbstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. A thermoresponsive, citrate-based macromolecule for bone regenerative engineering.Journal of biomedical materials research. Part A · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Robert van LithBiomedical Engineering Department, Northwestern University, Evanston, Illinois 60208, United States.
Xuesong WangBiomedical Engineering Department, Northwestern University, Evanston, Illinois 60208, United States.
Guillermo AmeerBiomedical Engineering Department, Northwestern University, Evanston, Illinois 60208, United States; Department of Surgery, Feinberg School of Medicine, Chicago, Illinois 60611, United States; Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois 60208, United States; Simpson Querrey Institute for BioNanotechnology in Medicine, Northwestern University, Chicago, Illinois 60611, United States; International Institute for Nanotechnology, Northwestern University, Evanston, Illinois 60208, United States.
Northwestern University · US

Funding

Preclinical Investigation of a Bioengineered Vascular GraftR01EB017129 · NIBIB · NORTHWESTERN UNIVERSITY · PI AMEER, GUILLERMO ANTONIO, KIBBE, MELINA RAE · 2013 to 2016
$1.8M
NIBIB NIH HHS R01 EB017129
6 · The paper itself

Abstract

Intimal hyperplasia (IH) is a type of scarring that involves complex pathophysiological responses of the vasculature to injury, including overproliferation and migration of vascular smooth muscle cells (VSMCs), adventitial fibroblasts, and the activation of macrophages. The objective of this research was to develop a biodegradable polymer with intrinsic properties that would combat the cellular processes that contribute to IH. Citric acid, 1,8-octanediol, and all-trans retinoic acid (atRA) were incorporated into a polyester network via a condensation reaction to form the thermoset poly(1,8-octamethylene-citrate-

Indexed as

all-trans retinoic acidcitric acidelastomerintimal hyperplasiavitamin A

Identifiers

PMID27347559
PMCPMC4916929
OpenAlexW2237461340

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.