Evidence map›Paper›PMID 27347489›Full record

ArticleScandinavian journal of child and adolescent psychiatry and psychology2016

Behavioral Weight Loss Treatment in Antipsychotic Treated Youth.

Ginger E Nicol, Rachel P Kolko, Monica Mills, Thrudur Gunnarsdottir, Michael D Yingling, Julia A Schweiger, Eric J Lenze, John W Newcomer, Denise Wilfley

Open access · diamondAbstract read
In one paragraph

Article in Scandinavian journal of child and adolescent psychiatry and psychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ginger E NicolHealthy Mind Lab, Department of Psychiatry, Washington University School of Medicine, St. Louis MO.
Rachel P KolkoDepartment of Psychiatry, Western Psychiatric Institute, University of Pittsburgh Medical Center, Pittsburgh, PA.
Monica MillsHealthy Mind Lab, Department of Psychiatry, Washington University School of Medicine, St. Louis MO.
Thrudur GunnarsdottirDepartment of Psychology, University of Akureyri, Iceland.
Michael D YinglingHealthy Mind Lab, Department of Psychiatry, Washington University School of Medicine, St. Louis MO.
Julia A SchweigerHealthy Mind Lab, Department of Psychiatry, Washington University School of Medicine, St. Louis MO.
Eric J LenzeHealthy Mind Lab, Department of Psychiatry, Washington University School of Medicine, St. Louis MO.
John W NewcomerWeight Management & Eating Disorders Program, Department of Psychiatry, Washington University School of Medicine, St. Louis MO.
Denise WilfleyWeight Management & Eating Disorders Program, Department of Psychiatry, Washington University School of Medicine, St. Louis MO; Department of Psychology, Washington University School of Medicine, St. Louis, MO; Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO; Department of Pediatrics, Washington University School of Medicine, St. Louis MO.
Florida Atlantic University · USUniversity of Akureyri · ISUniversity of Pittsburgh Medical Center · US

Funding

Washington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
Measurement of Cardiometabolic Risk in Antipsychotic-Treated ChildrenK23MH092435 · NIMH · WASHINGTON UNIVERSITY · PI NICOL, GINGER E · 2011 to 2015
$816k
NCATS NIH HHS UL1 TR000448NCRR NIH HHS UL1 RR024992NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK056341NIMH NIH HHS K23 MH092435
6 · The paper itself

Abstract

backgroundAntipsychotic-treated youth have increased risk for the development of obesity and type 2 diabetes. Behavioral weight loss treatments show promise in reducing obesity and diabetes risk in antipsychotic treated adults, but have received no study in antipsychotic treated youth.

objectiveWe describe a rationale for behavioral weight loss interventions in high-weight antipsychotic treated youth, and report behavioral, anthropomorphic, and metabolic findings from a case series of obese antipsychotic-treated adolescents participating in a short-term, family-based behavioral weight loss intervention.

methodsWe adapted the Traffic Light Plan, a 16-week family-based weight loss intervention that promotes healthy energy balance using the colors of the traffic light to categorize the nutritional value of foods and intensity of physical activity, adapting a social ecological framework to address health behavior change in multiple social contexts. The intervention was administered to three obese adolescents with long-term antipsychotic medication exposure. Efficacy of the intervention was evaluated with a battery of anthropomorphic and metabolic assessments including weight, body mass index percentile, whole body adiposity, liver fat content, and fasting plasma glucose and lipids. Participants and their parents also filled out a treatment satisfaction questionnaire upon study completion.

resultsTwo males and 1 female (all aged 14 years) participated. All 3 participants attended all 16 sessions, and experienced beneficial changes in adiposity, fasting lipids and liver fat content associated with weight stabilization or weight loss. Adolescents and their parents all reported a high level of satisfaction with the treatment.

conclusionsFamily-based behavioral weight loss treatment can be feasibly delivered and is acceptable to antipsychotic-treated youth and their families. Randomized controlled trials are needed to fully evaluate the effectiveness and acceptability of behavioral weight loss interventions in antipsychotic treated youth and their families.

Indexed as

AntipsychoticAt-Risk YouthPediatric ObesityWeight Loss Treatment

Identifiers

PMID27347489
PMCPMC4916921
OpenAlexW2375520864

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.