Evidence map›Paper›PMID 27347304›Full record

ReviewAmerican journal of translational research2016

MicroRNAs in laryngeal cancer: implications for diagnosis, prognosis and therapy.

Pei Li, Hui Liu, Zhiyuan Wang, Feng He, Haifeng Wang, Zhi Shi, Ankui Yang, Jin Ye

Open access · greenAbstract readReview
PubMed Full text at PMC
In one paragraph

Review in American journal of translational research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Laryngeal cancer diagnosis via miRNA-based decision tree model.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  7. Article
  8. Article
  9. LncRNAIranian journal of public health · 2021
    Article
  10. Article
  11. Article
  12. Identification of prognostic immune genes in laryngeal cancer.The Journal of international medical research · 2020
    Article
  13. MicroRNA-892a regulates laryngocarcinoma cell proliferation via Dicer.Experimental biology and medicine (Maywood, N.J.) · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Pei LiDepartment of Otolaryngology-Head and Neck Surgery, The Third Affiliated Hospital, Sun Yat-sen University Guangzhou, Guangdong, China.
Hui LiuDivision of Pulmonary and Critical Care, Department of Internal Medicine, The Third Affiliated Hospital, Sun Yat-sen University Guangzhou, Guangdong, China.
Zhiyuan WangDepartment of Otolaryngology-Head and Neck Surgery, The Third Affiliated Hospital, Sun Yat-sen University Guangzhou, Guangdong, China.
Feng HeDepartment of Otolaryngology-Head and Neck Surgery, The Third Affiliated Hospital, Sun Yat-sen University Guangzhou, Guangdong, China.
Haifeng WangDepartment of Otolaryngology-Head and Neck Surgery, The Third Affiliated Hospital, Sun Yat-sen University Guangzhou, Guangdong, China.
Zhi ShiDepartment of Cell Biology & Institute of Biomedicine, National Engineering Research Center of Genetic Medicine, Guangdong Provincial Key Laboratory of Bioengineering Medicine, College of Life Science and Technology, Jinan University Guangzhou, Guangdong, China.
Ankui YangDepartment of Head and Neck, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine Guangzhou, Guangdong, China.
Jin YeDepartment of Otolaryngology-Head and Neck Surgery, The Third Affiliated Hospital, Sun Yat-sen University Guangzhou, Guangdong, China.
Sun Yat-sen University · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laryngeal cancer is the most common head and neck cancer (skin excluded) with the increasing rates of morbidity and mortality in the world. The emerging roles of microRNAs (miRs) in laryngeal cancer have been deeply investigated in recent years. Deregulated miRs are frequently detected in tissues and cells of laryngeal cancer, which work as oncogenes or tumor supressors to regulate cancer cell proliferation, metastasis and invasion, etc. Here we reviewed the recognized roles of miRs in the diagnosis, prognosis and therapy of laryngeal cancer. Although there are lots of challenges in miRs including sensitivity, specificity, accuracy and safety, the growing improvements of miRs in laryngeal cancer remain encouraging and promising.

Indexed as

diagnosislaryngeal cancerMicroRNAsprognosistherapy

Identifiers

PMID27347304
PMCPMC4891409
OpenAlexW2465803133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.