Evidence map›Paper›PMID 27347264›Full record

ArticleThe open neuroimaging journal2016

The Chief Role of Frontal Operational Module of the Brain Default Mode Network in the Potential Recovery of Consciousness from the Vegetative State: A Preliminary Comparison of Three Case Reports.

Alexander A Fingelkurts, Andrew A Fingelkurts, Sergio Bagnato, Cristina Boccagni, Giuseppe Galardi

Open access · diamondAbstract read
In one paragraph

Article in The open neuroimaging journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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  3. The self and conscious experience.Frontiers in psychology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Alexander A FingelkurtsBM-Science - Brain and Mind Technologies Research Centre, Espoo, Finland.
Andrew A FingelkurtsBM-Science - Brain and Mind Technologies Research Centre, Espoo, Finland.
Sergio BagnatoNeurorehabilitation Unit, Rehabilitation Department, Fondazione Istituto "San Raffaele - G. Giglio", Cefalù (PA), Italy; Neurophysiology Unit, Rehabilitation Department, Fondazione Istituto "San Raffaele - G. Giglio", Cefalù (PA), Italy.
Cristina BoccagniNeurorehabilitation Unit, Rehabilitation Department, Fondazione Istituto "San Raffaele - G. Giglio", Cefalù (PA), Italy; Neurophysiology Unit, Rehabilitation Department, Fondazione Istituto "San Raffaele - G. Giglio", Cefalù (PA), Italy.
Giuseppe GalardiNeurorehabilitation Unit, Rehabilitation Department, Fondazione Istituto "San Raffaele - G. Giglio", Cefalù (PA), Italy; Neurophysiology Unit, Rehabilitation Department, Fondazione Istituto "San Raffaele - G. Giglio", Cefalù (PA), Italy.
Fondazione Istituto G. Giglio di Cefalù · ITBM-Science · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been argued that complex subjective sense of self is linked to the brain default-mode network (DMN). Recent discovery of heterogeneity between distinct subnets (or operational modules - OMs) of the DMN leads to a reconceptualization of its role for the experiential sense of self. Considering the recent proposition that the frontal DMN OM is responsible for the first-person perspective and the sense of agency, while the posterior DMN OMs are linked to the continuity of 'I' experience (including autobiographical memories) through embodiment and localization within bodily space, we have tested in this study the hypothesis that heterogeneity in the operational synchrony strength within the frontal DMN OM among patients who are in a vegetative state (VS) could inform about a stable self-consciousness recovery later in the course of disease (up to six years post-injury). Using EEG operational synchrony analysis we have demonstrated that among the three OMs of the DMN only the frontal OM showed important heterogeneity in VS patients as a function of later stable clinical outcome. We also found that the frontal DMN OM was characterized by the process of active uncoupling (stronger in persistent VS) of operations performed by the involved neuronal assemblies.

Indexed as

Alpha rhythmDefault-mode networkDMNEEGElectroencephalogramFirst-person perspectiveFunctional connectivityOperational synchronySubjective sense of selfUnresponsive wakefulness syndromeVegetative state

Identifiers

PMID27347264
PMCPMC4894863
OpenAlexW2348920469

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.