Evidence map›Paper›PMID 27347211›Full record

ArticleOncology letters2016

Methylation status of the

Dimitrios Matthaios, Ioanna Balgkouranidou, Anastasios Karayiannakis, Helen Bolanaki, Nikolaos Xenidis, Kyriakos Amarantidis, Leonidas Chelis, Konstantinos Romanidis, Aikaterini Chatzaki, Evi Lianidou and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Circulating Cell-Free DNA and Colorectal Cancer: A Systematic Review.International journal of molecular sciences · 2018
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Cell-Free DNA Hypermethylation in Patients with Acute Pancreatitis.International journal of molecular sciences · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Correlation betweenJournal of oncology · 2022
    Review
  13. Review
  14. Aberrant Promoter Hypermethylation ofIndian journal of surgical oncology · 2021
    Article
  15. Review
  16. Review
  17. Article
  18. Cell-Free DNA: Hope and Potential Application in Cancer.Frontiers in cell and developmental biology · 2021
    Review
  19. Frontiers in oncology · 2021
    Review
  20. APC Promoter Hypermethylation as a Prognostic Marker in Breast Cancer Patients.Asian Pacific journal of cancer prevention : APJCP · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Dimitrios MatthaiosDepartment of Medical Oncology, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, Alexandroupolis 68100, Greece.
Ioanna BalgkouranidouDepartment of Medical Oncology, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, Alexandroupolis 68100, Greece.
Anastasios KarayiannakisSecond Department of Surgery, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, Alexandroupolis 68100, Greece.
Helen BolanakiSecond Department of Surgery, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, Alexandroupolis 68100, Greece.
Nikolaos XenidisDepartment of Medical Oncology, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, Alexandroupolis 68100, Greece.
Kyriakos AmarantidisDepartment of Medical Oncology, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, Alexandroupolis 68100, Greece.
Leonidas ChelisDepartment of Medical Oncology, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, Alexandroupolis 68100, Greece.
Konstantinos RomanidisSecond Department of Surgery, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, Alexandroupolis 68100, Greece.
Aikaterini ChatzakiLaboratory of Pharmacology, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, Alexandroupolis 68100, Greece.
Evi LianidouLaboratory of Analytical Chemistry, Department of Chemistry, University of Athens, Athens 15771, Greece.
Grigorios TrypsianisLaboratory of Statistics, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, Alexandroupolis 68100, Greece.
Stylianos KakolyrisDepartment of Medical Oncology, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, Alexandroupolis 68100, Greece.
Democritus University of Thrace · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation is the most frequent epigenetic alteration. Using methylation-specific polymerase chain reaction (MSP), the methylation status of the adenomatous polyposis coli (

Indexed as

APCcell-free DNAcolon cancerDNA methylationRASSF1A

Identifiers

PMID27347211
PMCPMC4907278
OpenAlexW2417930447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.