Evidence map›Paper›PMID 27346995›Full record

ArticleClinical practice and epidemiology in mental health : CP & EMH2016

Quality of Life in Carotid Atherosclerosis: The Role of Co-morbid Mood Disorders.

Maria Lecca, Luca Saba, Roberto Sanfilippo, Elisa Pintus, Michela Cadoni, Federica Sancassiani, Maria Francesca Moro, Davide Craboledda, Chiara Lo Giudice, Roberto Montisci

Open access · hybridAbstract read
In one paragraph

Article in Clinical practice and epidemiology in mental health : CP & EMH, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Takotsubo Syndrome and Electroconvulsive Therapy: Time for Rigorous Assessment.Clinical practice and epidemiology in mental health : CP & EMH · 2019
    Article
  5. Article
  6. The Burden of Depressive and Bipolar Disorders in Celiac Disease.Clinical practice and epidemiology in mental health : CP & EMH · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Maria LeccaDepartment of Public Health and Clinical and Molecular Medicine and Center for Liaison Psychiatry and Psychoso-mathics, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari, Italy.
Luca SabaDepartment of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari, Italy.
Roberto SanfilippoDepartment of Surgical Sciences, Università di Cagliari, Italy.
Elisa PintusDepartment of Public Health and Clinical and Molecular Medicine and Center for Liaison Psychiatry and Psychoso-mathics, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari, Italy.
Michela CadoniDepartment of Public Health and Clinical and Molecular Medicine and Center for Liaison Psychiatry and Psychoso-mathics, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari, Italy.
Federica SancassianiDepartment of Public Health and Clinical and Molecular Medicine and Center for Liaison Psychiatry and Psychoso-mathics, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari, Italy.
Maria Francesca MoroDepartment of Public Health and Clinical and Molecular Medicine and Center for Liaison Psychiatry and Psychoso-mathics, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari, Italy.
Davide CraboleddaDepartment of Surgical Sciences, Università di Cagliari, Italy.
Chiara Lo GiudiceDepartment of Surgical Sciences, Università di Cagliari, Italy.
Roberto MontisciDepartment of Surgical Sciences, Università di Cagliari, Italy.
Azienda Ospedaliero-Universitaria Cagliari · ITUniversity of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION/

objectiveTo study in severe carotid atherosclerosis (CA): the frequency of mood disorders (MD); the impairment of quality of life (QoL); the role of co-morbid MD in such impairment.

methodsCase-control study. CASES: consecutive in-patients with CA (stenosis ≥ 50%). CONTROLS: subjects with no diagnosis of CA randomized from a database of a community survey. Psychiatric diagnosis according to DSM-IV made by clinicians and semi-structured interview, QoL measured by the Short Form Health Survey (SF-12).

resultsThis is the first study on comorbidity on CA disease and MD in which psychiatric diagnoses are conducted by clinicians according to DSM-IV diagnostic criteria. Major Depressive Disorder (MDD) (17.4% vs 2.72%, P <0.0001) but not Bipolar Disorders (BD) (4.3% vs 0.5%, P = 0.99) was higher in cases (N=46) than in controls (N= 184). SF-12 scores in cases were lower than in controls (30.56±8.12 vs 36.81±6:40; p <0.001) with QoL comparable to serious chronic diseases of the central nervous system. The burden of a concomitant MDD or BD amplifies QoL impairment.

conclusionComorbid MD aggravates the impairment of QoL in CA. Unlike autoimmune diseases or degenerative diseases of the Central Nervous System, CA shows a strong risk of MDD than BD.

Indexed as

Bipolar disordercarotid atherosclerosismajor depressive disordermood disordersquality of life

Identifiers

PMID27346995
PMCPMC4797686
OpenAlexW2293584960

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.