Evidence map›Paper›PMID 27346983›Full record

ArticleMacromolecular materials and engineering2015

Microwave-Assisted Preparation of Hydrogel-Forming Microneedle Arrays for Transdermal Drug Delivery Applications.

Eneko Larrañeta, Rebecca E M Lutton, Aaron J Brady, Eva M Vicente-Pérez, A David Woolfson, Raghu Raj Singh Thakur, Ryan F Donnelly

Abstract read
In one paragraph

Article in Macromolecular materials and engineering, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Swellable Microneedles in Drug Delivery and Diagnostics.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eneko LarrañetaChair in Pharmaceutical Technology School of Pharmacy Queens University Belfast, Medical Biology Centre 97 Lisburn Road Belfast BT9 7BL UK.
Rebecca E M LuttonChair in Pharmaceutical Technology School of Pharmacy Queens University Belfast, Medical Biology Centre 97 Lisburn Road Belfast BT9 7BL UK.
Aaron J BradyChair in Pharmaceutical Technology School of Pharmacy Queens University Belfast, Medical Biology Centre 97 Lisburn Road Belfast BT9 7BL UK.
Eva M Vicente-PérezChair in Pharmaceutical Technology School of Pharmacy Queens University Belfast, Medical Biology Centre 97 Lisburn Road Belfast BT9 7BL UK.
A David WoolfsonChair in Pharmaceutical Technology School of Pharmacy Queens University Belfast, Medical Biology Centre 97 Lisburn Road Belfast BT9 7BL UK.
Raghu Raj Singh ThakurChair in Pharmaceutical Technology School of Pharmacy Queens University Belfast, Medical Biology Centre 97 Lisburn Road Belfast BT9 7BL UK.
Ryan F DonnellyChair in Pharmaceutical Technology School of Pharmacy Queens University Belfast, Medical Biology Centre 97 Lisburn Road Belfast BT9 7BL UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

1A microwave (MW)-assisted crosslinking process to prepare hydrogel-forming microneedle (MN) arrays was evaluated. Conventionally, such MN arrays are prepared using processes that includes a thermal crosslinking step. Polymeric MN arrays were prepared using poly(methyl vinyl ether-alt-maleic acid) crosslinked by reaction with poly(ethylene glycol) over 24 h at 80 °C. Polymeric MN arrays were prepared to compare conventional process with the novel MW-assisted crosslinking method. Infrared spectroscopy was used to evaluate the crosslinking degree, evaluating the area of the carbonyl peaks (2000-1500 cm

Indexed as

crosslinkinghydrogelsmicroneedlemicrowavestransdermal drug delivery

Identifiers

PMID27346983
PMCPMC4862021

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.