ArticleThe Laryngoscope2016
Smoking cessation is associated with improved survival in oropharynx cancer treated by chemoradiation.
Article in The Laryngoscope, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Pooled it
- Impact of Smoking on the Survival of Patients With High-risk HPV-positive HNSCC: A Meta-analysis.In vivo (Athens, Greece)Pooled it
- Head and neck squamous cell carcinoma: current and emerging therapeutic strategies.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Review
- Ferroptosis-activating metabolite acrolein antagonizes necroptosis and anti-cancer therapeutics.Nature communications · 2025Article
- Severe Oral Mucositis After Intensity-Modulated Radiation Therapy for Head and Neck Cancer.JAMA network open · 2023Article
- Patterns of cigarette smoking and alcohol drinking among Canadian adults with cancer in a contemporary national cohort.Journal of cancer survivorship : research and practice · 2023Article
- Smoking Cessation after Cancer Diagnosis and Enhanced Therapy Response: Mechanisms and Significance.Current oncology (Toronto, Ont.) · 2022Review
- Association of Pack-Years of Cigarette Smoking With Survival and Tumor Progression Among Patients Treated With Chemoradiation for Head and Neck Cancer.JAMA network open · 2022Article
- A practical guide for perioperative smoking cessation.Journal of anesthesia · 2022Review
- The characteristics of patients who quit smoking in the year following a cancer diagnosis.Journal of cancer survivorship : research and practice · 2022Article
- Incidence and survival in laryngeal and lung cancers in Finland and Sweden through a half century.PloS one · 2022Article
- It Takes Two to Tango: Patients' and Providers' Perspectives in Tobacco Cessation and Head/Neck Cancer.The oncologist · 2021Article
- De-Escalated Adjuvant Therapy After Transoral Robotic Surgery for Human Papillomavirus-Related Oropharyngeal Carcinoma: The Sinai Robotic Surgery (SIRS) Trial.The oncologist · 2021Article
- Matched pair analysis for comparison of survival outcome of alternative regimens to standard three-weekly cisplatin-based concurrent chemoradiation of head and neck cancer.Annals of translational medicine · 2021Article
- Article
- Squamous cell carcinoma of the head and neck with unknown primary: trends and outcomes from a hospital-based registry.Annals of translational medicine · 2021Article
- Matched pair analysis to evaluate the impact of hospitalization during radiation therapy as an early marker of survival in head and neck cancer patients.Oral oncology · 2020Article
- Impact of a tobacco treatment program on abstinence and survival rates among current smokers with head and neck squamous cell carcinoma.Head & neck · 2020Article
- Article
- Genetic Variants Were Associated With the Prognosis of Head and Neck Squamous Carcinoma.Frontiers in oncology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 1 institution in 1 country.
Funding
Abstract
objectives/hypothesisThe effect of smoking and human papillomavirus (HPV) on overall survival (OS) of oropharyngeal squamous cell carcinoma (OPSCC) patients undergoing concurrent chemotherapy (CCRT) remains unclear. STUDY
designRetrospective review.
methodsClinical characteristics of OPSCC patients treated between 2008 and 2015 with CCRT were abstracted from medical records. OS curves and multivariate cox proportional hazard ratios (HRs) were examined.
resultsOf 120 evaluable patients, 71% had HPV
conclusionsCurrent smoking is associated with poor prognosis, independent of HPV status, in CCRT-treated OPSCC patients. Current smoking produced an approximately four- to sevenfold increase in risk of mortality for HPV LEVEL OF EVIDENCE: 4. Laryngoscope, 126:2733-2738, 2016.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.