ArticleNature communications2016
Mechanisms of increased Trichodesmium fitness under iron and phosphorus co-limitation in the present and future ocean.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 89 citations in OpenAlex.
- Article
- Flake-Shaped Nickel Hydroxide Supported on Carbon Cloth as an Electrochemical Sensor for Efficient Detection of Phosphate Under Neutral Conditions.Sensors (Basel, Switzerland) · 2025Article
- Trichodesmium metaproteomes reflect the differential influence of resource availability across ocean regions.The ISME journal · 2025Article
- Phosphorus deficiency alleviates iron limitation in Synechocystis cyanobacteria through direct PhoB-mediated gene regulation.Nature communications · 2024Article
- Flexible BProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Interactions between the nitrogen-fixing cyanobacteriumISME communications · 2024Article
- Proteomics analysis reveals differential acclimation of coastal and oceanicFrontiers in microbiology · 2024Article
- A critical role for iron and zinc homeostatic systems in the evolutionary adaptation ofMicrobial genomics · 2023Article
- Integrating the impact of global change on the niche and physiology of marine nitrogen-fixing cyanobacteria.Global change biology · 2022Article
- Molecular mechanisms underlying iron and phosphorus co-limitation responses in the nitrogen-fixing cyanobacterium Crocosphaera.The ISME journal · 2022Article
- Phosphate limitation intensifies negative effects of ocean acidification on globally important nitrogen fixing cyanobacterium.Nature communications · 2022Article
- The marine nitrogen cycle: new developments and global change.Nature reviews. Microbiology · 2022Review
- Why Environmental Biomarkers Work: Transcriptome-Proteome Correlations and Modeling of Multistressor Experiments in the Marine BacteriumJournal of proteome research · 2022Article
- Exploring Variability ofFrontiers in microbiology · 2022Article
- Long-Term m5C Methylome Dynamics Parallel Phenotypic Adaptation in the Cyanobacterium Trichodesmium.Molecular biology and evolution · 2021Article
- Exploring biogeochemical and ecological redundancy in phytoplankton communities in the global ocean.Global change biology · 2021Article
- Microbial evolutionary strategies in a dynamic ocean.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Proteomic responses to ocean acidification of the marine diazotroph Trichodesmium under iron-replete and iron-limited conditions.Photosynthesis research · 2019Article
- Climate-driven oscillation of phosphorus and iron limitation in the North Pacific Subtropical Gyre.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- CO2 modulation of the rates of photosynthesis and light-dependent O2 consumption in Trichodesmium.Journal of experimental botany · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitrogen fixation by cyanobacteria supplies critical bioavailable nitrogen to marine ecosystems worldwide; however, field and lab data have demonstrated it to be limited by iron, phosphorus and/or CO2. To address unknown future interactions among these factors, we grew the nitrogen-fixing cyanobacterium Trichodesmium for 1 year under Fe/P co-limitation following 7 years of both low and high CO2 selection. Fe/P co-limited cell lines demonstrated a complex cellular response including increased growth rates, broad proteome restructuring and cell size reductions relative to steady-state growth limited by either Fe or P alone. Fe/P co-limitation increased abundance of a protein containing a conserved domain previously implicated in cell size regulation, suggesting a similar role in Trichodesmium. Increased CO2 further induced nutrient-limited proteome shifts in widespread core metabolisms. Our results thus suggest that N2-fixing microbes may be significantly impacted by interactions between elevated CO2 and nutrient limitation, with broad implications for global biogeochemical cycles in the future ocean.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.