ArticleTrends in molecular medicine2016
Zika in the Brain: New Models Shed Light on Viral Infection.
Article in Trends in molecular medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Zika virus infection in neonatal mice disrupts connexin 43 and induces cardiac inflammation, implicating viral myocarditis in neonatal pathogenesis.Journal of virology · 2025Article
- The function of immunomodulation and biomaterials for scaffold in the process of bone defect repair: A review.Frontiers in bioengineering and biotechnology · 2023Review
- Neurodevelopmental outcome of infants without central nervous system anomalies born to symptomatic RT-PCR ZIKV positive women.PLoS neglected tropical diseases · 2022Observational
- Development and Expression of Subunit Vaccines Against Viruses in Plants.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Zika Virus Overview: Transmission, Origin, Pathogenesis, Animal Model and Diagnosis.Zoonoses (Shannon, Ireland) · 2021Article
- Zika virus increases mind bomb 1 levels, causing degradation of pericentriolar material 1 (PCM1) and dispersion of PCM1-containing granules from the centrosome.The Journal of biological chemistry · 2019Article
- Postnatal Zika virus infection of nonhuman primate infants born to mothers infected with homologous Brazilian Zika virus.Scientific reports · 2019Article
- Zika Virus Infects Trabecular Meshwork and Causes Trabeculitis and Glaucomatous Pathology in Mouse Eyes.mSphere · 2019Article
- Zika Virus Fatally Infects Wild Type Neonatal Mice and Replicates in Central Nervous System.Viruses · 2018Article
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Authors and funding
2 authors.
Funding
Abstract
The current Zika virus (ZIKV) outbreak is associated with high numbers of human congenital birth defects, yet it has been unclear how ZIKV infection during pregnancy causes these abnormalities. Three new mouse models now show that ZIKV crosses the placenta and replicates in the brains of fetal mice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.