Evidence map›Paper›PMID 27345590›Full record

ArticleScientific reports2016

Mobile phone imaging and cloud-based analysis for standardized malaria detection and reporting.

Thomas F Scherr, Sparsh Gupta, David W Wright, Frederick R Haselton

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Recent Applications of Artificial Intelligence in Discovery of New Antibacterial Agents.Advances and applications in bioinformatics and chemistry : AABC · 2024
    Review
  10. Article
  11. Innovations in3 Biotech · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas F ScherrDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN.
Sparsh GuptaDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN.
David W WrightDepartment of Chemistry, Vanderbilt University, Nashville, TN.
Frederick R HaseltonDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN.

Funding

Vanderbilt-Zambia Network for Innovation in Global Health TechnologiesD43TW009348 · FIC · VANDERBILT UNIVERSITY · PI HASELTON, FREDERICK R, HEIMBURGER, DOUGLAS CORBETT · 2012 to 2016
$1.7M
FIC NIH HHS D43 TW009348
6 · The paper itself

Abstract

Rapid diagnostic tests (RDTs) have been widely deployed in low-resource settings. These tests are typically read by visual inspection, and accurate record keeping and data aggregation remains a substantial challenge. A successful malaria elimination campaign will require new strategies that maximize the sensitivity of RDTs, reduce user error, and integrate results reporting tools. In this report, an unmodified mobile phone was used to photograph RDTs, which were subsequently uploaded into a globally accessible database, REDCap, and then analyzed three ways: with an automated image processing program, visual inspection, and a commercial lateral flow reader. The mobile phone image processing detected 20.6 malaria parasites/microliter of blood, compared to the commercial lateral flow reader which detected 64.4 parasites/microliter. Experienced observers visually identified positive malaria cases at 12.5 parasites/microliter, but encountered reporting errors and false negatives. Visual interpretation by inexperienced users resulted in only an 80.2% true negative rate, with substantial disagreement in the lower parasitemia range. We have demonstrated that combining a globally accessible database, such as REDCap, with mobile phone based imaging of RDTs provides objective, secure, automated, data collection and result reporting. This simple combination of existing technologies would appear to be an attractive tool for malaria elimination campaigns.

Indexed as

Cell PhoneCloud ComputingImage Processing, Computer-AssistedMalaria, FalciparumMobile ApplicationsPlasmodium falciparumErythrocytesHumans

Identifiers

PMID27345590
PMCPMC4921854

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.