ReviewBirth defects research. Part C, Embryo today : reviews2016
Cocaine-induced neurodevelopmental deficits and underlying mechanisms.
Review in Birth defects research. Part C, Embryo today : reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Pooled it
- Brain-Derived Exosomes in Neurodevelopmental and Neuropsychiatric Disorders: Molecular Insights, Therapeutic Potential, and Translational Challenges.Molecular neurobiology · 2025Review
- Talking to Your Patients About Alcohol, Marijuana, and Substance Use During Pregnancy.The primary care companion for CNS disorders · 2025Article
- Illicit substance exposure in pregnancy and infant mortality risk: a nationwide Taiwan study.The international journal of neuropsychopharmacology · 2025Article
- Mothers with Concurrent Opioid and Cocaine Use and Neonatal Opioid Withdrawal Syndrome.Children (Basel, Switzerland) · 2025Article
- Evaluation of histological and ultrastructural changes provoked by prenatal tramadol on postnatal cortical cerebellar neuronal development in rats: possible implication of Ki67, GFAP and MicroRNA-7/P53 signalling trajectories.Journal of molecular histology · 2024Article
- Prenatal cocaine exposure and self-reported behavioral adjustments from ages 12 to 21: environmental pathways.Psychological medicine · 2024Article
- Perinatal Psychoactive Substances Use: A Rising Perinatal Mental Health Concern.Journal of clinical medicine · 2023Review
- Prenatal cannabis use and its impact on offspring neuro-behavioural outcomes: A systematic review.Paediatrics & child health · 2023Article
- Prenatal cocaine exposure and substance use disorder in emerging adulthood at age 21.Drug and alcohol dependence · 2023Article
- Psychotropic drug abuse in pregnancy and its impact on child neurodevelopment: A review.World journal of clinical pediatrics · 2022Review
- Prenatal methamphetamine exposure causes dysfunction in glucose metabolism and low birthweight.Frontiers in endocrinology · 2022Article
- Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants.The EMBO journal · 2020Article
- Prenatal Environment That Affects Neuronal Migration.Frontiers in cell and developmental biology · 2019Review
- Reversal Learning Deficits Associated with Increased Frontal Cortical Brain-Derived Neurotrophic Factor Tyrosine Kinase B Signaling in a Prenatal Cocaine Exposure Mouse Model.Developmental neuroscience · 2016Article
- Cognitive and functional outcomes at age 21 after prenatal cocaine/polydrug exposure and foster/adoptive care.Neurotoxicology and teratologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Exposure to drugs early in life has complex and long-lasting implications for brain structure and function. This review summarizes work to date on the immediate and long-term effects of prenatal exposure to cocaine. In utero cocaine exposure produces disruptions in brain monoamines, particularly dopamine, during sensitive periods of brain development, and leads to permanent changes in specific brain circuits, molecules, and behavior. Here, we integrate clinical studies and significance with mechanistic preclinical studies, to define our current knowledge base and identify gaps for future investigation. Birth Defects Research (Part C) 108:147-173, 2016. © 2016 Wiley Periodicals, Inc.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.