ArticleJournal of biomechanics2016
3D MRI-based multicomponent thin layer structure only plaque models for atherosclerotic plaques.
Article in Journal of biomechanics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Comparison and identification of human coronary plaques with/without erosion using patient-specific optical coherence tomography-based fluid-structure interaction models: a pilot study.Biomechanics and modeling in mechanobiology · 2025Article
- Non-invasive estimation of material properties of normal and dissected human ascending aortasFrontiers in bioengineering and biotechnology · 2025Article
- Macrophages in cardiac remodelling after myocardial infarction.Nature reviews. Cardiology · 2023Review
- Combining IVUS + OCT Data, Biomechanical Models and Machine Learning Method for Accurate Coronary Plaque Morphology Quantification and Cap Thickness and Stress/Strain Index Predictions.Journal of functional biomaterials · 2023Article
- Image-Based Finite Element Modeling Approach for Characterizing In Vivo Mechanical Properties of Human Arteries.Journal of functional biomaterials · 2022Review
- Multi-patient study for coronary vulnerable plaque model comparisons: 2D/3D and fluid-structure interaction simulations.Biomechanics and modeling in mechanobiology · 2021Article
- Rupture Risk Assessment of Cervical Spinal Manipulations on Carotid Atherosclerotic Plaque by a 3D Fluid-Structure Interaction Model.BioMed research international · 2021Article
- Quantifying Patient-SpecificFrontiers in physiology · 2021Article
- Consideration of stiffness of wall layers is decisive for patient-specific analysis of carotid artery with atheroma.PloS one · 2020Article
- Vulnerable Plaque, Characteristics, Detection, and Potential Therapies.Journal of cardiovascular development and disease · 2019Review
- Coronary Atherosclerotic Plaque Vulnerability Rather than Stenosis Predisposes to Non-ST Elevation Acute Coronary Syndromes.Cardiology research and practice · 2019Article
- Coronary Atherosclerotic Vulnerable Plaque: Current Perspectives.Journal of the American Heart Association · 2017Review
- Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
MRI-based fluid-structure interactions (FSI) models for atherosclerotic plaques have been developed to perform mechanical analysis to investigate the association of plaque wall stress (PWS) with cardiovascular disease. However, the time consuming 3D FSI model construction process is a great hinder for its clinical implementations. In this study, a 3D thin-layer structure only (TLS) plaque model was proposed as an approximation with much less computational cost to 3D FSI models for better clinical implementation potential. 192 TLS models were constructed based on 192 ex vivo MRI Images of 12 human coronary atherosclerotic plaques. Plaque stresses were extracted from all lumen nodal points. The maximum value of Plaque wall stress (MPWS) and average value of plaque wall stress (APWS) of each slice were used to compare with those from corresponding FSI models. The relative errors for MPWS and APWS were 9.76% and 9.89%, respectively. Both MPWS and APWS values obtained from TLS models showed very good correlation with those from 3D FSI models. Correlation results from TLS models were in consistent with FSI models. Our results indicated that the proposed 3D TLS plaque models may be used as a good approximation to 3D FSI models with much less computational cost. With further validation, 3D TLS models may be possibly used to replace FSI models to save time and perform mechanical analysis for atherosclerotic plaques for clinical implementation.
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Registered trials
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