ArticleAmerican journal of preventive medicine2016
Influence of Age and Comorbidity on Colorectal Cancer Screening in the Elderly.
Article in American journal of preventive medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Use of NCCN Guidelines, Other Guidelines, and Biomarkers for Colorectal Cancer Screening.Journal of the National Comprehensive Cancer Network : JNCCN · 2016Guideline
- The influence of multi-morbidities on colorectal cancer screening recommendations and completion.Cancer causes & control : CCC · 2021Trial
- Sociodemographic and Clinical Predictors of Colonoscopy Utilization in Oman: A Call to Action within a Population-Based Cross-Sectional Study.Asian Pacific journal of cancer prevention : APJCP · 2026Article
- eHealth literacy and cancer screening attitudes among chronic patients.Scientific reports · 2025Article
- Article
- Optimization of colorectal cancer screening strategies: New insights.World journal of gastroenterology · 2024Article
- Improving Colorectal Cancer Screening in a Regional Safety-Net Health System over a 10-Year Period: Lessons for Population Health.Journal of general internal medicine · 2024Observational
- Adherence to follow-up and resource use after abnormal FIT-screening: Evaluation of the Danish colorectal cancer screening program.Endoscopy international open · 2024Article
- Overdiagnosis of hepatocellular carcinoma: Prevented by guidelines?Hepatology (Baltimore, Md.) · 2022Review
- Trends of cancer incidence among Chinese older adults from 2005 to 2016: A log-linear regression and age-period-cohort analysis.Frontiers in public health · 2022Article
- Colorectal cancer and potential predictors of never screened for faecal occult blood test: a narrative review.Journal of public health research · 2021Article
- Disparities in colorectal cancer screening among breast and prostate cancer survivors.Cancer medicine · 2021Article
- ANALYSES OF PREVENTIVE CARE MEASURES WITH INCOMPLETE HISTORICAL DATA IN ELECTRONIC MEDICAL RECORDS: AN EXAMPLE FROM COLORECTAL CANCER SCREENING.The annals of applied statistics · 2020Article
- Screening Mammography Outcomes: Risk of Breast Cancer and Mortality by Comorbidity Score and Age.Journal of the National Cancer Institute · 2020Article
- Evaluating Screening Participation, Follow-up, and Outcomes for Breast, Cervical, and Colorectal Cancer in the PROSPR Consortium.Journal of the National Cancer Institute · 2020Article
- Initiation of Colorectal Cancer Screening Among Medicaid Enrollees.American journal of preventive medicine · 2020Article
- Variation in Colorectal Cancer Stage and Mortality across Large Community-Based Populations: PORTAL Colorectal Cancer Cohort.The Permanente journal · 2020Article
- Comorbid chronic diseases and cancer diagnosis: disease-specific effects and underlying mechanisms.Nature reviews. Clinical oncology · 2019Review
- Frailty Assessment Predicts Acute Outcomes in Patients Undergoing Screening Colonoscopy.Digestive diseases and sciences · 2018Article
- Overdiagnosis: An Understudied Issue in Hepatocellular Carcinoma Surveillance.Seminars in liver disease · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 9 institutions in 1 country.
Funding
Abstract
introductionExpert recommendations differ for colorectal cancer screening in the elderly. Recent studies suggest that healthy adults aged >75 years may benefit from screening. This study examined screening use and follow-up, and how they varied by health status within age strata, among a large cohort of elderly individuals in community settings.
methodsA population-based, longitudinal cohort study was conducted among health plan members aged 65-89 years enrolled during 2011-2012 in three integrated healthcare systems participating in the Population-Based Research Optimizing Screening through Personalized Regimens consortium. Comorbidity measurements used the Charlson index. Analyses, conducted in 2015, comprised descriptive statistics and multivariable modeling that estimated age by comorbidity-specific percentages of patients for two outcomes: colorectal cancer screening uptake and follow-up of abnormal fecal blood tests.
resultsAmong 846,267 patients, 72% were up-to-date with colorectal cancer screening. Of patients with a positive fecal blood test, 65% received follow-up colonoscopy within 3 months. Likelihood of being up-to-date and receiving timely follow-up was significantly lower for patients aged ≥76 years than their younger counterparts (p<0.001). Comorbidity was less influential than age and more strongly related to timely follow-up than being up-to-date. In all age groups, considerable numbers of patients with no/low comorbidity were not up-to-date or did not receive timely follow-up.
conclusionsIn three integrated healthcare systems, many older, relatively healthy patients were not screening up-to-date, and some relatively young, healthy patients did not receive timely follow-up. Findings suggest a need for re-evaluating age-based screening guidelines and improving screening completion among the elderly.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.