ArticleSocial cognitive and affective neuroscience2016
Inferior fronto-temporo-occipital connectivity: a missing link between maltreated girls and neglectful mothers.
Article in Social cognitive and affective neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 52 citations in OpenAlex.
- Characterising Maternal Sensitivity in a High Risk, Peri-urban LMIC Context: The Drakenstein Child Health Study.Child psychiatry and human development · 2026Article
- Maternal epigenetic index links early neglect to later neglectful care and other psychopathological, cognitive, and bonding effects.Clinical epigenetics · 2025Article
- Psychometric analysis of the emotional availability scales for video-recorded interactions between parents and their preschool-aged children.Frontiers in child and adolescent psychiatry · 2025Article
- Neuroanatomical changes observed over the course of a human pregnancy.Nature neuroscience · 2024Article
- Editorial: Neural and Epigenetic Factors in Parenting, Individual Differences and Dyadic Processes.Brain sciences · 2022Article
- The shared mother-child epigenetic signature of neglect is related to maternal adverse events.Frontiers in physiology · 2022Article
- Improving Early Diagnosis of Child Neglect for a Better Response in Healthcare Settings.Children (Basel, Switzerland) · 2021Article
- Neurobiological Implications of Parent-Child Emotional Availability: A Review.Brain sciences · 2021Review
- A structural brain network of genetic vulnerability to psychiatric illness.Molecular psychiatry · 2021Article
- Distinctive Frontal and Occipitotemporal Surface Features in Neglectful Parenting.Brain sciences · 2021Article
- How stress can influence brain adaptations to motherhood.Frontiers in neuroendocrinology · 2021Review
- White matter microstructure mediates the association between prenatal exposure to phthalates and behavior problems in preschool children.Environmental research · 2020Article
- Limbic-visual attenuation to crying faces underlies neglectful mothering.Scientific reports · 2019Article
- Childhood Trauma Associated White Matter Abnormalities in First-Episode Schizophrenia.Schizophrenia bulletin · 2019Article
- Anatomical and Neurochemical Correlates of Parental Verbal Abuse: A Combined MRS-Diffusion MRI Study.Frontiers in human neuroscience · 2019Article
- Childhood Emotional Abuse Moderates Associations Among Corticomotor White Matter Structure and Stress Neuromodulators in Women With and Without Depression.Frontiers in neuroscience · 2018Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neurobiological alterations resulting from adverse childhood experiences that subsequently may lead to neglectful mothering are poorly understood. Maternal neglect of an infant's basic needs is the most prevalent type of child maltreatment. We tested white matter alterations in neglectful mothers, the majority of whom had also suffered maltreatment in their childhood, and compared them to a matched control group. The two groups were discriminated by a structural brain connectivity pattern comprising inferior fronto-temporo-occipital connectivity, which constitutes a major portion of the face-processing network and was indexed by fewer streamlines in neglectful mothers. Mediation and regression analyses showed that fewer streamlines in the right inferior longitudinal fasciculus tract (ILF-R) predicted a poorer quality of mother-child emotional availability observed during cooperative play and that effect depended on the respective interactions with left and right inferior fronto-occipital fasciculi (IFO-R/L), with no significant impact of psychopathological and cognitive conditions. Volume alteration in ILF-R but not in IFO-L modulated the impact of having been maltreated on emotional availability. The findings suggest the altered inferior fronto-temporal-occipital connectivity, affecting emotional visual processing, as a possible common neurological substrate linking a history of childhood maltreatment with maternal neglect.
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