ArticleBMC medicine2016
Real-world data in the United Kingdom: opportunities and challenges.
Article in BMC medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Fluocinolone acetonide vitreous insert for chronic diabetic macular oedema: a systematic review with meta-analysis of real-world experience.Scientific reports · 2021Pooled it
- Harnessing routinely collected data for the evaluation of early years interventions: insights from a scoping review of evaluation studies.International journal of population data science · 2026Article
- Operationalising routinely collected patient data in research to further the pursuit of social justice and health equity: a team-based scoping review.BMC medical research methodology · 2025Article
- Article
- [Research advances of real world study in the field of chronic wound].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022Article
- Key Learnings from Running an Extension Study to a Real-World Effectiveness Trial: The Extended Salford Lung Study.Advances in therapy · 2021Article
- [Need for real-world data studies on hidradenitis suppurativa/acne inversa treatment].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2021Review
- Moving Auto-Correlation Window Approach for Heart Rate Estimation in Ballistocardiography Extracted by Mattress-Integrated Accelerometers.Sensors (Basel, Switzerland) · 2020Article
- Can real-world data really replace randomised clinical trials?BMC medicine · 2020Article
- Patient-Community Perspectives on Real-World Evidence: Enhancing Engagement, Understanding, and Trust.The patient · 2019Article
- Information and Communication Technologies, a Promising Way to Support Pharmacotherapy for the Behavioral and Psychological Symptoms of Dementia.Frontiers in pharmacology · 2019Article
- Endovascular treatment outcomes using the Stroke Triage Education, Procedure Standardization, and Technology (STEPS-T) program.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2018Article
- Time to really share real-world data?F1000Research · 2018Article
- Real-world data really matter.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017Article
- An analysis of characteristics of post-authorisation studies registered on the ENCePP EU PAS Register.F1000Research · 2017Article
- From Population Databases to Research and Informed Health Decisions and Policy.Frontiers in public health · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Real-world data is that collected outside the constraints of controlled clinical trials and is increasingly informing decision-making in healthcare. The landscape of real-world data in the United Kingdom is set to evolve over the coming months as the government plans to build on databases currently in place by collecting patient data from all family practices and linking this information with hospital records. This initiative, called care.data, has the potential to be an invaluable resource. However, the programme has been criticized on grounds of data privacy, which has led to an extended delay in its implementation and the expectation that a large number of people will opt out. Opt-outs may introduce substantial biases to the dataset, and understanding how to account for these presents a significant challenge for researchers. For the scope and quality of real-world evidence in the United Kingdom to be realised, and for this information to be used effectively, it is essential to address this challenge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.