Evidence map›Paper›PMID 27342314›Full record

ArticleBehavioral and brain functions : BBF2016

Brain activation differences in schizophrenia during context-dependent processing of saccade tasks.

A L Rodrigue, B P Austin, K A Dyckman, J E McDowell

Abstract read
In one paragraph

Article in Behavioral and brain functions : BBF, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

A L RodrigueDepartment of Psychology, University of Georgia, Psychology Building 125 Baldwin Street, Athens, GA, 30602, USA.
B P AustinDepartment of Psychology, University of Georgia, Psychology Building 125 Baldwin Street, Athens, GA, 30602, USA.
K A DyckmanDepartment of Psychology, University of Georgia, Psychology Building 125 Baldwin Street, Athens, GA, 30602, USA.
J E McDowellDepartment of Psychology, University of Georgia, Psychology Building 125 Baldwin Street, Athens, GA, 30602, USA. jemcd@uga.edu.

Funding

Neural circuitry plasticity resulting from saccadic practice in schizophreniaR03MH076998 · NIMH · UNIVERSITY OF GEORGIA · PI MCDOWELL, JENNIFER E · 2007 to 2008
$148k
NIMH NIH HHS R03 MH076998
6 · The paper itself

Abstract

backgroundBrain function in schizophrenia has been probed using saccade paradigms and functional magnetic resonance imaging, but little information exists about how changing task context impacts saccade related brain activation and behavioral performance. We recruited schizophrenia and comparison subjects to perform saccade tasks in differing contexts: (1) two single task runs (anti- or pro-saccades alternating with fixation) and (2) one dual task run (antisaccades alternating with prosaccades).

resultsContext-dependent differences in saccade circuitry were evaluated using ROI analyses. Distinction between anti- and pro-saccade activation across contexts (single versus dual task) suggests that the schizophrenia group did not respond to context in the same way as the comparison group.

conclusionsFurther investigation of context processing effects on brain activation and saccade performance measures informs models of cognitive deficits in the disorder and enhances understanding of antisaccades as a potential endophenotype for schizophrenia.

Indexed as

AdultBrainBrain MappingEye MovementsFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPhotic StimulationReaction TimeSaccadesSchizophreniaAntisaccadesContextfMRIProsaccadesSchizophrenia

Identifiers

PMID27342314
PMCPMC4919833

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.