Evidence map›Paper›PMID 27342301›Full record

Trial reportJournal of pediatric psychology2017

Long-Term Efficacy of Computerized Cognitive Training Among Survivors of Childhood Cancer: A Single-Blind Randomized Controlled Trial.

Heather M Conklin, Jason M Ashford, Kellie N Clark, Karen Martin-Elbahesh, Kristina K Hardy, Thomas E Merchant, Robert J Ogg, Sima Jeha, Lu Huang, Hui Zhang

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of pediatric psychology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06312969 (Cognitive Training Through Technological Gaming To Ameliorate Cognitive Effects Related To Childhood Cancer Treatment), which is not on this map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06312969 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Cognitive Training Through Technological Gaming To Ameliorate Cognitive Effects Related To Childhood Cancer Treatment (WINNERS)

TypeinterventionalSponsorAntonio Pérez MartínezRan2023 to 2025Enrolled56ConditionsSurvivors of Childhood CancerArmsVideo game based training
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Heather M ConklinDepartment of Psychology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Jason M AshfordDepartment of Psychology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Kellie N ClarkDepartment of Psychology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Karen Martin-ElbaheshDepartment of Psychology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Kristina K HardyNeuropsychology Division, Center for Neuroscience and Behavioral Medicine, Children's National Medical Center, Washington, DC, USA.
Thomas E MerchantDepartment of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Robert J OggDivision of Translational Imaging, St. Jude Children's Research Hospital, Memphis, TN, USA.
Sima JehaDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Lu HuangDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA.
Hui ZhangDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA.

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
NCI NIH HHS P30 CA021765
6 · The paper itself

Abstract

Objective: To investigate the long-term efficacy of computerized cognitive training in improving cognitive outcomes among childhood cancer survivors. Methods: Sixty-eight survivors of childhood acute lymphoblastic leukemia (ALL) or brain tumor (BT) were randomly assigned to computerized cognitive intervention (23 ALL/11 BT, age = 12.21 ± 2.47) or a waitlist control group (24 ALL/10 BT, age = 11.82 ± 2.42). Cognitive assessments were completed pre-, immediately post-, and 6 months postintervention. Results: A prior report showed training led to immediate improvement in working memory, attention and processing speed. In the current study, piecewise linear mixed effects modeling revealed that working memory and processing speed were unchanged from immediate to 6 months postintervention (intervention β  = -.04 to .01, p = .26 to .95; control β  = -.06 to .01, p = .23-.97), but group differences on an attention measure did not persist. Conclusion: Cognitive benefits are maintained 6 months following computerized cognitive training, adding to potential clinical utility of this intervention approach.

Indexed as

Brain NeoplasmsChildCognition DisordersFemaleFollow-Up StudiesHumansMalePrecursor Cell Lymphoblastic Leukemia-LymphomaSingle-Blind MethodSurvivorsTherapy, Computer-AssistedTimebrain tumorcomputerized cognitive trainingleukemiapediatricworking memory

Identifiers

PMID27342301
PMCPMC5896595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.