Evidence map›Paper›PMID 27342260›Full record

ArticleMagnetic resonance in medicine2017

Impact of transcytolemmal water exchange on estimates of tissue microstructural properties derived from diffusion MRI.

Hua Li, Xiaoyu Jiang, Jingping Xie, John C Gore, Junzhong Xu

Open access · bronzeAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 73 citations in OpenAlex.

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  15. Joint estimation of compartment-specific TMagnetic resonance in medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hua LiInstitute of Imaging Science, Vanderbilt University, Nashville, Tennessee, USA.
Xiaoyu JiangInstitute of Imaging Science, Vanderbilt University, Nashville, Tennessee, USA.
Jingping XieInstitute of Imaging Science, Vanderbilt University, Nashville, Tennessee, USA.
John C GoreInstitute of Imaging Science, Vanderbilt University, Nashville, Tennessee, USA.
Junzhong XuInstitute of Imaging Science, Vanderbilt University, Nashville, Tennessee, USA.
Vanderbilt University · US

Funding

Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
MRI Diffusion in Tumors Using Oscillating GradientsR01CA109106 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI XU, JUNZHONG · 2006 to 2022
$4.0M
Comprehensive Evaluation of OGSE DWI for Assessing Tumor Treatment ResponseR01CA173593 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GORE, JOHN C · 2013 to 2017
$1.3M
Assessment of Tumor Early Response to Treatment by Diffusion MRIK25CA168936 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI XU, JUNZHONG · 2013 to 2017
$728k
NCI NIH HHS K25 CA168936NCI NIH HHS R01 CA109106NCI NIH HHS R01 CA173593NICHD NIH HHS U54 HD083211
6 · The paper itself

Abstract

purposeTo investigate the influence of transcytolemmal water exchange on estimates of tissue microstructural parameters derived from diffusion MRI using conventional PGSE and IMPULSED methods.

methodsComputer simulations were performed to incorporate a broad range of intracellular water life times τ

resultsSimulations showed that, for both PGSE and IMPULSED methods, cell diameter d can be reliably fit with sufficient SNR (≥ 50), whereas intracellular volume fraction f

conclusionFor the sequences and models considered in this study, transcytolemmal water exchange has minor effects on the fittings of d and D

Indexed as

ArtifactsAnimalsBody WaterCell Line, TumorCell MembraneCell Membrane PermeabilityDiffusion Magnetic Resonance ImagingMiceNeoplasms, ExperimentalReproducibility of ResultsSensitivity and Specificitycell sizediffusiondiffusion timeintracellularMRIOGSEtranscytolemmal water exchange

Identifiers

PMID27342260
PMCPMC5183568
OpenAlexW2468917515

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.