Evidence map›Paper›PMID 27342243›Full record

ReviewHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2016

Autonomic Dysfunction: How to Identify and When to Treat?

Francesca Saladini, Attilio Di Marco, Paolo Palatini

Abstract readReview
PubMed Publisher
In one paragraph

Review in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Vasovagal syncope: the role of 24 h ambulatory blood pressure monitoring.European heart journal supplements : journal of the European Society of Cardiology · 2026
    Article
  2. Survey on Office Blood Pressure Measurement in Daily Practice in the Hypertension Centers of the Italian Society of Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Article
  3. Article
  4. Article
  5. Predictors of Cardiac Autonomic Dysfunction in Obesity-Related Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Francesca SaladiniCardiology Unit, Town Hospital of Camposampiero, via Pietro Cosma 2, Camposampiero, Italy. francescasaladini@yahoo.it.
Attilio Di MarcoCardiology Unit, Town Hospital of Camposampiero, via Pietro Cosma 2, Camposampiero, Italy.
Paolo PalatiniVascular Medicine, Department of Medicine, University of Padova, via Giustiniani, 2, 35128, Padua, Italy.
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular autonomic dysfunction (AD) is a particular condition that can be detected by means of ambulatory blood pressure monitoring (ABPM). ABPM is helpful to identify some specific characteristics of haemodynamic AD, including non-dipping/reverse-dipping pattern, orthostatic and post-prandial hypotension and elevated blood pressure variability. These characteristics may be misdiagnosed with traditional, clinic blood pressure measurements. AD is relatively common in the real world. By analysing about 1000 recordings in a Cardiology unit, AD was found in 6.8 % of the exams. Several diseases may be the underlying causes of AD. In our sample half of the subjects were diabetic (54.4 %), 17.7 % were patients with alpha-synucleinopathy (Parkinson disease or multiple system atrophy), and 27.9 % had other underlying causes of AD including chronic kidney disease, α-lytic drug assumption and AD from unknown causes. According to the different aetiology, different clinical characteristics can be found, in particular in diabetics these peculiar aspects are less pronounced compared to the other subgroups. These characteristics have been found to be predictors of cardiovascular events, organ damage, and mortality. For these reasons, early identification of these behaviours is important, in order to better define patient's cardiovascular risk profile. As regard treatment of AD, several drugs have been tested, however none of this showed efficacy in all kinds of patients. Another open aspect is "safe" reference values for supine hypertension.

Indexed as

Blood Pressure Monitoring, AmbulatoryAgedAntihypertensive AgentsAutonomic Nervous SystemAutonomic Nervous System DiseasesBlood PressureCardiovascular SystemCircadian RhythmFemaleHumansHypertensionHypotension, OrthostaticMalePredictive Value of TestsPrognosisRisk FactorsAntihypertensive AgentsAutonomic dysfunctionOrthostatic hypotensionVariability

Identifiers

PMID27342243
OpenAlexW2474350022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.