ArticleEuropean journal of medicinal plants2016
Natural Products Screening for the Identification of Selective Monoamine Oxidase-B Inhibitors.
Article in European journal of medicinal plants, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 19 citations in OpenAlex.
- UnveilingInternational journal of molecular sciences · 2026Article
- Review of Pharmacotherapeutic Targets in Alzheimer's Disease and Its Management Using Traditional Medicinal Plants.Degenerative neurological and neuromuscular disease · 2024Review
- Roles of selected non-P450 human oxidoreductase enzymes in protective and toxic effects of chemicals: review and compilation of reactions.Archives of toxicology · 2022Review
- The Possible Therapeutic Effects of Some Medicinal Plants for Chronic Cough in Children.Evidence-based complementary and alternative medicine : eCAM · 2020Review
- Neuroprotective potency of some spice herbs, a literature review.Journal of traditional and complementary medicine · 2019Review
- The Benzopyrone Biochanin-A as a reversible, competitive, and selective monoamine oxidase B inhibitor.BMC complementary and alternative medicine · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
aimsMonoamine oxidase-B inhibitors (MAO-BIs) are used for the initial therapy of Parkinson's disease. Also, MAO-BIs have shown to be effective neuroprotective agents in several neurodegenerative diseases. However, some concerns exist regarding the long-term use of these compounds. Meanwhile, natural compounds showed potential MAO-B selective inhibitions. To date, few selective natural MAO-BIs have been identified. Therefore, the current study is designed to identify plants with potent and specific MAO-B inhibition. STUDY
designIn this work, we utilized high throughput screening to evaluate the different plants ethanolic extract for their effectiveness to inhibit METHODOLOGY: Recombinant human isozymes were verified by Western blotting, and the 155 plants were screened. A continuous fluorometric screening assay was performed followed by two separate
resultsIn the screened plants, 9% of the extracts showed more than 1.5-fold relative inhibition of
conclusionThe obtained results indicate that
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.