Evidence map›Paper›PMID 27341140›Full record

ArticleAJR. American journal of roentgenology2016

Semiautomated Segmentation of Polycystic Kidneys in T2-Weighted MR Images.

Timothy L Kline, Marie E Edwards, Panagiotis Korfiatis, Zeynettin Akkus, Vicente E Torres, Bradley J Erickson

Abstract read
In one paragraph

Article in AJR. American journal of roentgenology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
  2. State of the art review of AI in renal imaging.Abdominal radiology (New York) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Timothy L Kline1 Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.
Marie E Edwards2 Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN.
Panagiotis Korfiatis1 Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.
Zeynettin Akkus1 Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.
Vicente E Torres2 Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN.
Bradley J Erickson1 Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.

Funding

Pilot and FeasibilityP30DK090728 · NIDDK · MAYO CLINIC ROCHESTER · PI ROMERO, MICHAEL F. · 2010 to 2019
$11.8M
RENIN ANGIOTENSIN SYSTEM IN THE PATHOGENESIS OF ADPKDR01DK044863 · NIDDK · MAYO CLINIC ROCHESTER · PI TORRES, VICENTE E · 1991 to 2019
$4.5M
Objective decision support environment for clinical trialsU01CA160045 · NCI · MAYO CLINIC ROCHESTER · PI ERICKSON, BRADLEY J. · 2012 to 2016
$2.6M
NCI NIH HHS U01 CA160045NIDDK NIH HHS P30 DK090728NIDDK NIH HHS R01 DK044863
6 · The paper itself

Abstract

objectiveThe objective of the present study is to develop and validate a fast, accurate, and reproducible method that will increase and improve institutional measurement of total kidney volume and thereby avoid the higher costs, increased operator processing time, and inherent subjectivity associated with manual contour tracing. MATERIALS AND

methodsWe developed a semiautomated segmentation approach, known as the minimal interaction rapid organ segmentation (MIROS) method, which results in human interaction during measurement of total kidney volume on MR images being reduced to a few minutes. This software tool automatically steps through slices and requires rough definition of kidney boundaries supplied by the user. The approach was verified on T2-weighted MR images of 40 patients with autosomal dominant polycystic kidney disease of varying degrees of severity.

resultsThe MIROS approach required less than 5 minutes of user interaction in all cases. When compared with the ground-truth reference standard, MIROS showed no significant bias and had low variability (mean ± 2 SD, 0.19% ± 6.96%).

conclusionThe MIROS method will greatly facilitate future research studies in which accurate and reproducible measurements of cystic organ volumes are needed.

Indexed as

AdultAutomationFemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedOrgan SizePolycystic Kidney, Autosomal DominantReproducibility of ResultsSoftwareautosomal dominant polycystic kidney diseasegeodesic active contourplanimetrystereologytotal kidney volume

Identifiers

PMID27341140
PMCPMC5313045

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.