Evidence map›Paper›PMID 27340913›Full record

ArticleThe Clinical journal of pain2017

Clinical Phenotyping of Youth With New-Onset Musculoskeletal Pain: A Controlled Cohort Study.

Amy Lewandowski Holley, Anna C Wilson, Elise Cho, Tonya M Palermo

Open access · greenAbstract readControlled Clinical Trial
In one paragraph

Article in The Clinical journal of pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

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  14. A Model of the Intersection of Pain and Opioid Misuse in Children and Adolescents.Clinical psychological science : a journal of the Association for Psychological Science · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Amy Lewandowski Holley*Institute on Development & Disability, Oregon Health & Science University, Portland, OR †Seattle Children's Research Institute ‡Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA.
Anna C Wilson
Elise Cho
Tonya M Palermo
Oregon Health & Science University · USUniversity of Washington · US

Funding

Innovations in Pediatric Pain ResearchK24HD060068 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI PALERMO, TONYA M · 2009 to 2018
$1.6M
Chronic Pain in Pediatric Primary CareK23HD071946 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI LEWANDOWSKI HOLLEY, AMY S · 2012 to 2016
$583k
NICHD NIH HHS K23 HD071946NICHD NIH HHS K24 HD060068
6 · The paper itself

Abstract

objectivesThe course of pediatric musculoskeletal pain from acute to chronic has not been well described and there is limited understanding of how to identify individuals with new-onset pain who may be predisposed to developing persisting symptoms. Thus, the purpose of this study was to describe the clinical phonotype of treatment-seeking youth with new-onset musculoskeletal pain compared with youth with and without chronic pain. Further, we tested predictors of pain-related disability and pain sensitivity in the new-onset pain sample.

methodsParticipants were 191 youth, ages 10 to 17 years, representing 3 cohorts (new-onset musculoskeletal pain, chronic musculoskeletal pain, and a comparison group without chronic pain). Participants completed questionnaire measures of pain characteristics, psychological functioning, sleep, and pain-related disability. They also attended a laboratory visit to complete an experimental pain assessment using heat and cold stimuli to assess pain sensitivity and conditioned pain modulation.

resultsFindings revealed youth with new-onset musculoskeletal pain had a distinct clinical phenotype where symptoms of pain and disability were in the mid-range between those of youth with diagnosed chronic musculoskeletal pain and youth in the community without chronic pain. Linear regressions within the new-onset pain sample demonstrated poorer sleep quality and higher pain fear predicted greater pain-related disability, and pain catastrophizing predicted cold pressor sensitivity. DISCUSSION: Clinical phenotyping of youth with new-onset musculoskeletal pain highlights factors relevant to the pain experience. Future research can examine the roles of these variables in predicting longitudinal risk for chronic pain and disability.

Indexed as

Acute DiseaseAdolescentChildChronic PainDisability EvaluationFemaleHumansLinear ModelsLongitudinal StudiesMaleMusculoskeletal PainPain MeasurementPhenotypeSleepSurveys and Questionnaires

Identifiers

PMID27340913
PMCPMC5140689
OpenAlexW2472165614

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.