Evidence map›Paper›PMID 27340824›Full record

ArticlePloS one2016

A Fit-Fat Index for Predicting Incident Diabetes in Apparently Healthy Men: A Prospective Cohort Study.

Robert A Sloan, Benjamin A Haaland, Susumu S Sawada, I-Min Lee, Xuemei Sui, Duck-Chul Lee, Yassine Ridouane, Falk Müller-Riemenschneider, Steven N Blair

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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  13. Low Fitness and High Fatness: The "Double Whammy" on Vascular Health.Taehan Sup'och'u Uihakhoe chi = The Korean journal of sports medicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 3 countries.

Robert A SloanKagoshima University, Graduate Medical and Dental School, Department of Psychosomatic Internal Medicine, Kagoshima, Japan.
Benjamin A HaalandGeorgia Institute of Technology, H. Milton Stewart School of Industrial and Systems Engineering, Atlanta, Georgia, United States of America.
Susumu S SawadaNational Institute of Biomedical Innovation, Health and Nutrition, Department of Health Promotion and Exercise, Tokyo, Japan.
I-Min LeeHarvard University, Harvard T.H. Chan School of Public Health, Department of Epidemiology, Division of Preventive Medicine, Department of Medicine, and Brigham and Women's Hospital and Harvard Medical School, Boston and Cambridge, Massachusetts, United States of America.
Xuemei SuiUniversity of South Carolina, Arnold School of Public Health, Department of Exercise Science, Columbia, South Carolina, United States of America.
Duck-Chul LeeIowa State University, College of Human Sciences, Department of Kinesiology, Ames, Iowa, United States of America.
Yassine RidouaneGeorgia Institute of Technology, H. Milton Stewart School of Industrial and Systems Engineering, Atlanta, Georgia, United States of America.
Falk Müller-RiemenschneiderNational University of Singapore, Saw Swee Hock School of Public Health, Singapore.
Steven N BlairUniversity of South Carolina, Arnold School of Public Health, Department of Exercise Science, Columbia, South Carolina, United States of America.
Georgia Institute of Technology · USUniversity of South Carolina · USBrigham and Women's Hospital · USIowa State University · USKagoshima University · JPNational Institute of Biomedical Innovation, Health and Nutrition · JPNational University Health System · SG

Funding

Impact of Physical Fitness and Exercise on HealthR37AG006945 · NIA · COOPER INSTITUTE · PI BLAIR, STEVEN N. · 2002 to 2005
$2.7M
CORONARY ARTERY CALCIUM, EXERCISE TESTS, AND CHD OUTCOMER01HL062508 · NHLBI · COOPER INSTITUTE · PI LAMONTE, MICHAEL J · 1999 to 2004
$2.5M
IMPACT OF PHYSICAL FITNESS &EXERCISE ON HEALTHR01AG006945 · NIA · COOPER INSTITUTE · PI BLAIR, STEVEN N. · 1986 to 2001
$1.1M
Understanding Patterns of Change in Obesity and Physical Activity in AdultsR21DK088195 · NIDDK · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI SUI, XUEMEI · 2010 to 2011
$397k
NHLBI NIH HHS R01 HL062508NIA NIH HHS R01 AG006945NIA NIH HHS R37 AG006945NIDDK NIH HHS R21 DK088195
6 · The paper itself

Abstract

backgroundThe purpose of this study was to examine the impact of combined cardiorespiratory fitness and waist-to-height ratio in the form of a fit-fat index on incident diabetes risk. Additionally, the independent predictive performance of cardiorespiratory fitness, waist-to-height ratio, and body mass index also were estimated and compared.

methodsThis was a prospective cohort study of 10,381 men who had a normal electrocardiogram and no history of major chronic disease at baseline from 1979 to 2005. Random survival forest models and traditional Cox proportional hazards models were used to predict diabetes at 5-, 10-, and 15-year incidence horizons.

resultsOverall, 4.8% of the participants developed diabetes. Receiver operating characteristic curve analyses for incidence risk demonstrated good discrimination using random survival forest models across fitness and fatness measures; Cox models were poor to fair. The differences between fitness and fatness measures across horizons were clinically negligible. Smoothed random survival forest estimates demonstrated the impact of each fitness and fatness measure on incident diabetes was intuitive and graded.

conclusionsAlthough fitness and fatness measures showed a similar discriminative ability in predicting incident diabetes, unique to the study was the ability of the fit-fat index to demonstrate a better indication of incident risk when compared to fitness or fatness alone. A single index combining cardiorespiratory fitness and waist-to-height ratio may be more useful because it can indicate improvements in either or both of the measures.

Indexed as

Cardiorespiratory FitnessWaist-Height RatioAdultArea Under CurveDiabetes MellitusFollow-Up StudiesHumansIncidenceMaleMiddle AgedProportional Hazards ModelsProspective StudiesRisk Factors

Identifiers

PMID27340824
PMCPMC4920380
OpenAlexW2463017605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.