ArticleCartilage2015
Next Generation Mesenchymal Stem Cell (MSC)-Based Cartilage Repair Using Scaffold-Free Tissue Engineered Constructs Generated with Synovial Mesenchymal Stem Cells.
Article in Cartilage, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Next-Generation Cartilage Repair: Clinical Use of Wharton's Jelly MSCs and the Emerging Role of AI-Assisted Bioprinting.Bioengineering (Basel, Switzerland) · 2026Review
- Comparative analysis of scaffold-free tissue-engineered cartilage derived from different seed cells: in vitro and in vivo studies.Stem cells translational medicine · 2025Article
- Advanced therapy with mesenchymal stromal cells for knee osteoarthritis: Systematic review and meta-analysis of randomized controlled trials.Journal of orthopaedic translation · 2024Review
- A novel scaffold-free mesenchymal stem cell-derived tissue engineered construct for articular cartilage restoration - From basic to clinic.Regenerative therapy · 2024Review
- Rapid Recovery after Reparation of Full-Thickness Chondral Defects of the Knee with the Use of Hyaluronan (HA)-Based 3-D Scaffold.Journal of functional biomaterials · 2023Article
- Five-Year Outcomes After Implantation of a Scaffold-Free Tissue-Engineered Construct Generated From Autologous Synovial Mesenchymal Stromal Cells for Repair of Knee Chondral Lesions.Orthopaedic journal of sports medicine · 2023Article
- [Surgical treatment of focal cartilage defects in the knee : Indications, techniques, modifications and results].Der Orthopade · 2022Article
- Perspectives on Stem Cell-Based Regenerative Medicine with a Particular Emphasis on Mesenchymal Stem Cell Therapy.JMA journal · 2022Review
- Editorial: Tissue Engineering and Cell Therapy for Cartilage Restoration.Frontiers in cell and developmental biology · 2022Article
- Anti-hypertrophic effect of synovium-derived stromal cells on costal chondrocytes promotes cartilage repairs.Journal of orthopaedic translation · 2022Article
- Article
- [Surgical treatment of focal cartilage defects in the knee : Indications, techniques, modifications and results].Zeitschrift fur Rheumatologie · 2021Article
- Perspective: Challenges Presented for Regeneration of Heterogeneous Musculoskeletal Tissues that Normally Develop in Unique Biomechanical Environments.Frontiers in bioengineering and biotechnology · 2021Review
- Synovial membrane mesenchymal stem cells: past life, current situation, and application in bone and joint diseases.Stem cell research & therapy · 2020Review
- Macrophage: A Potential Target on Cartilage Regeneration.Frontiers in immunology · 2020Review
- Toward zonally tailored scaffolds for osteochondral differentiation of synovial mesenchymal stem cells.Journal of biomedical materials research. Part B, Applied biomaterials · 2019Article
- Human Synovial Mesenchymal Stem Cells Good Manufacturing Practices for Articular Cartilage Regeneration.Tissue engineering. Part C, Methods · 2018Article
- Development of a Novel Large Animal Model to Evaluate Human Dental Pulp Stem Cells for Articular Cartilage Treatment.Stem cell reviews and reports · 2018Article
- Dental Pulp Stem Cell-Derived, Scaffold-Free Constructs for Bone Regeneration.International journal of molecular sciences · 2018Article
- Synthesis of photo-reactive poly (vinyl alcohol) and construction of scaffold-free cartilage like pelletsRegenerative biomaterials · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Because of its limited healing capacity, treatments for articular cartilage injuries are still challenging. Since the first report by Brittberg, autologous chondrocyte implantation has been extensively studied. Recently, as an alternative for chondrocyte-based therapy, mesenchymal stem cell-based therapy has received considerable research attention because of the relative ease in handling for tissue harvest, and subsequent cell expansion and differentiation. This review summarizes latest development of stem cell therapies in cartilage repair with special attention to scaffold-free approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.