ReviewBeilstein journal of organic chemistry2016
Biosynthesis of α-pyrones.
Review in Beilstein journal of organic chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Mechanistic profiling and optimized production of Altenusin, a fungal carboxy-biphenyl scaffold for tyrosinase inhibition.RSC advances · 2026Article
- Genome mining reveals the distribution of biosynthetic gene clusters in Alternaria and related fungal taxa within the family Pleosporaceae.BMC genomics · 2025Article
- An Overview of α-Pyrones as Phytotoxins Produced by Plant Pathogen Fungi.Molecules (Basel, Switzerland) · 2025Review
- Rare Chlorinated Fungal Metabolite and Alpha-Pyrones from an Endophytic Fungus Nigrospora sp.ACS omega · 2025Article
- Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway.Cell chemical biology · 2025Article
- Facile construction of 2-pyrones under carbene catalysis.RSC advances · 2024Review
- Regioselective Annulation of 6-Carboxy-Substituted Pyrones as a Two-Carbon Unit in Formal [4 + 2] Cycloaddition Reactions.The Journal of organic chemistry · 2024Article
- Demonstrating the Applicability of Proton Transfer Reaction Mass Spectrometry to Quantify Volatiles Emitted by the Mycoparasitic FungusJournal of the American Society for Mass Spectrometry · 2024Article
- Natural resorcylic lactones derived from alternariol.Beilstein journal of organic chemistry · 2024Review
- Biosynthesis-Guided Discovery and Engineering of α-Pyrone Natural Products from Type I Polyketide Synthases.ACS chemical biology · 2023Article
- Naturally Occurring Organohalogen Compounds-A Comprehensive Review.Progress in the chemistry of organic natural products · 2023Review
- Secondary Metabolites and Biosynthetic Gene Clusters Analysis of Deep-Sea Hydrothermal Vent-DerivedMarine drugs · 2022Article
- Discovery of prescopranone, a key intermediate in scopranone biosynthesis.The Journal of antibiotics · 2022Article
- Biosynthesis and biological function of secondary metabolites of the rice blast fungus Pyricularia oryzae.Journal of industrial microbiology & biotechnology · 2021Review
- Secondary Metabolites ofMolecules (Basel, Switzerland) · 2021Review
- Defueling the cancer: ATP synthase as an emerging target in cancer therapy.Molecular therapy oncolytics · 2021Review
- Emergence of 2-Pyrone and Its Derivatives, from Synthesis to Biological Perspective: An Overview and Current Status.Topics in current chemistry (Cham) · 2021Review
- A formal [3 + 3] cycloaddition of allenyl imide and activated ketones for the synthesis of tetrasubstituted 2-pyrones.RSC advances · 2021Article
- Divergent rhodium-catalyzed electrochemical vinylic C-H annulation of acrylamides with alkynes.Nature communications · 2021Article
- CRISPR-Cas9-Based Discovery of the Verrucosidin Biosynthesis Gene Cluster inFrontiers in microbiology · 2021Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The α-pyrone moiety is a structural feature found in a huge variety of biologically active metabolites. In recent times new insights into additional biosynthetic mechanisms, yielding in such six-membered unsaturated ester ring residues have been obtained. The purpose of this mini-review is to give a brief overview of α-pyrones and the mechanisms forming the basis of their natural synthesis. Especially the chain interconnecting enzymes, showing homology to ketosynthases which catalyze Claisen-like condensation reactions, will be presented.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.