ReviewBeilstein journal of organic chemistry2016
(Thio)urea-mediated synthesis of functionalized six-membered rings with multiple chiral centers.
Review in Beilstein journal of organic chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- The impact of supramolecular self-association of organocatalysts on catalytic performance.Nature reviews. Chemistry · 2025Review
- Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity.Molecules (Basel, Switzerland) · 2022Review
- Synthesis of Isothiocyanates Using DMT/NMM/TsOMolecules (Basel, Switzerland) · 2021Article
- New Mesoporous Silica-Supported Organocatalysts Based on (2Molecules (Basel, Switzerland) · 2020Article
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3 authors.
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Abstract
Organocatalysis, now running its second decade of life, is being considered one of the main tools a synthetic chemist has to perform asymmetric catalysis. In this review the synthesis of six-membered rings, that contain multiple chiral centers, either by a ring closing process or by a functionalization reaction on an already existing six-membered ring, utilizing bifunctional (thio)ureas will be summarized. Initially, the use of primary amine-thioureas as organocatalysts for the above transformation is being discussed, followed by the examples employing secondary amine-thioureas. Finally, the use of tertiary amine-thioureas and miscellaneous examples are presented.
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