ReviewAustralian prescriber2016
Bone mineral density: testing for osteoporosis.
Review in Australian prescriber, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 3 syntheses or guidelines pooled it, 135 citations in OpenAlex.
- Meta-analysis of bone mineral density in adults with phenylketonuria.Orphanet journal of rare diseases · 2024Pooled it
- Machine learning algorithms for diagnosis of hip bone osteoporosis: a systematic review and meta-analysis study.Biomedical engineering online · 2023Pooled it
- Effect of oral and transdermal oestrogen therapy on bone mineral density in functional hypothalamic amenorrhoea: a systematic review and meta-analysis.BMJ open sport & exercise medicine · 2021Pooled it
- Long-term efficacy and safety of mitapivat in non-transfusion-dependent α- or β-thalassaemia: An open-label phase 2 study.British journal of haematology · 2025Trial
- Blackcurrants Reduce the Risk of Postmenopausal Osteoporosis: A Pilot Double-Blind, Randomized, Placebo-Controlled Clinical Trial.Nutrients · 2022Trial
- Diffuse Bilateral Multifocal Bone Stress Injuries in a 19-Year-Old Male Military Trainee: A Case Report.Cureus · 2026Article
- Unlocking forensic potential: machine learning-driven estimation of sex, age, and stature from proximal femur using dual-energy X-ray absorptiometry.International journal of legal medicine · 2026Article
- Xylosyltransferase-I serum activity is a promising biomarker for postmenopausal osteoporosis.Scientific reports · 2026Article
- Advancing osteoporosis opportunistic screening: multicenter validation of a deep learning algorithm using abdominal CT scans.Abdominal radiology (New York) · 2026Article
- A bone optimization rheumatology clinic increases anabolic bone agent use and reduces mechanical complications in adult spinal deformity surgery.Spine deformity · 2026Article
- Article
- Normative data and standardized scores for sarcopenia indicators in middle-aged and older adults: a large screening-based cohort study.Osteoporosis and sarcopenia · 2026Article
- Canal-to-Bone Ratio as an Independent Predictor of Hip Bone Mineral Density Scores: A Retrospective Analysis.The Eurasian journal of medicine · 2026Article
- Sex and age specific bone mineral density trends in Sri Lankan adults support the need for normative reference data.Frontiers in endocrinology · 2026Article
- Physical Activity Trajectories and Bone Mineral Density in Adults: Indirect Associations of Skeletal Muscle Mass and Body Fat.Calcified tissue international · 2025Article
- Diagnostic Imaging of the Skeletal System: Overview of Applications in Human and Veterinary Medicine.Bioengineering (Basel, Switzerland) · 2025Review
- Anterior cement augmentation technique for correction of kyphotic deformity in the lumbar spine using an anterior-to-Psoas approach.North American Spine Society journal · 2025Article
- Deciphering subsidence risk after ACDF: a biomechanical study on bone density and endplate thickness.BMC musculoskeletal disorders · 2025Article
- The Diagnostic Accuracy of Biological Markers of Sarcopenia, Sarcopenic Obesity, and Osteosarcopenia: Protocol for a Systematic Review and Meta-Analysis.Health science reports · 2025Article
- Metabolomic evaluation of air pollution-related bone damage and potential mediation in Women's Health Initiative participants.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary osteoporosis is related to bone loss from ageing. Secondary osteoporosis results from specific conditions that may be reversible. A thoracolumbar X-ray is useful in identifying vertebral fractures, and dual energy X-ray absorptiometry is the preferred method of calculating bone mineral density. The density of the total hip is the best predictor for a hip fracture, while the lumbar spine is the best site for monitoring the effect of treatment. The T-score is a comparison of the patient's bone density with healthy, young individuals of the same sex. A negative T-score of -2.5 or less at the femoral neck defines osteoporosis. The Z-score is a comparison with the bone density of people of the same age and sex as the patient. A negative Z-score of -2.5 or less should raise suspicion of a secondary cause of osteoporosis. Clinical risk calculators can be used to predict the 10-year probability of a hip or major osteoporotic fracture. A probability of more than 5% for the hip or more than 20% for any fracture is abnormal and treatment may be warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.