Evidence map›Paper›PMID 27339952›Full record

ArticleAJNR. American journal of neuroradiology2016

Evaluating Instantaneous Perfusion Responses of Parotid Glands to Gustatory Stimulation Using High-Temporal-Resolution Echo-Planar Diffusion-Weighted Imaging.

T-W Chiu, Y-J Liu, H-C Chang, Y-H Lee, J-C Lee, K Hsu, C-W Wang, J-M Yang, H-H Hsu, C-J Juan

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In one paragraph

Article in AJNR. American journal of neuroradiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

T-W ChiuFrom the Departments of Radiology (T.-W.C., C.-W.W., H.-H.H., C.-J.J.).ORCID http://orcid.org/0000-0002-1636-279X
Y-J LiuDepartment of Medicine (T.-W.C.), Taipei Medical University, Taipei, Taiwan.ORCID http://orcid.org/0000-0001-5865-6836
H-C ChangDepartment of Diagnostic Radiology (H.-C.C.), The University of Hong Kong, Hong Kong.ORCID http://orcid.org/0000-0003-3546-9194
Y-H LeeDepartment of Medicine (T.-W.C.), Taipei Medical University, Taipei, Taiwan.ORCID http://orcid.org/0000-0003-1010-1131
J-C LeeDepartment of Otolaryngology-Head and Neck Surgery (J.-C.L.), Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.ORCID http://orcid.org/0000-0002-4950-0239
K HsuDentistry (K.H.), National Defense Medical Center, Taipei, Taiwan.ORCID http://orcid.org/0000-0002-8351-161X
C-W WangFrom the Departments of Radiology (T.-W.C., C.-W.W., H.-H.H., C.-J.J.).ORCID http://orcid.org/0000-0002-4288-1729
J-M YangDepartment of Biological Science and Technology (J.-C.L., J.-M.Y.), Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, Taiwan.ORCID http://orcid.org/0000-0002-3205-4391
H-H HsuFrom the Departments of Radiology (T.-W.C., C.-W.W., H.-H.H., C.-J.J.).ORCID http://orcid.org/0000-0003-4485-8247
C-J JuanFrom the Departments of Radiology (T.-W.C., C.-W.W., H.-H.H., C.-J.J.) peterjuancj@yahoo.com.tw.ORCID http://orcid.org/0000-0001-5219-0406

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeParotid glands secrete and empty saliva into the oral cavity rapidly after gustatory stimulation. However, the role of the temporal resolution of DWI in investigating parotid gland function remains uncertain. Our aim was to design a high-temporal-resolution echo-planar DWI pulse sequence and to evaluate the instantaneous MR perfusion responses of the parotid glands to gustatory stimulation. MATERIALS AND

methodsThis prospective study enrolled 21 healthy volunteers (M/F = 2:1; mean age, 45.2 ± 12.9 years). All participants underwent echo-planar DWI (total scan time, 304 seconds; temporal resolution, 4 s/scan) on a 1.5T MR imaging scanner. T2WI (

resultsAlmost perfect interobserver agreement was achieved (κ ≥ 0.656). The parotid glands had magnetic susceptibility artifacts in 14.3% (3 of 21) of volunteers during swallowing on DWI but were free from perceptible artifacts at the baseline and at the end of scans on all images. Increased ADC and reduced signal intensity of the parotid glands on T2WI and DWI occurred immediately after oral administration of lemon juice. Maximal signal change of ADC (24.8% ± 10.8%) was significantly higher than that of T2WI (-10.1% ± 5.2%,

conclusionsInstantaneous parotid perfusion responses to gustatory stimulation can be quantified by ADC by using high-temporal-resolution echo-planar DWI.

Identifiers

PMID27339952
PMCPMC7960459

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.