Evidence map›Paper›PMID 27339420›Full record

ReviewJournal of nanobiotechnology2016

Application prospective of nanoprobes with MRI and FI dual-modality imaging on breast cancer stem cells in tumor.

Hetao Chen, Yu Wang, Tong Wang, Dongxing Shi, Zengrong Sun, Chunhui Xia, Baiqi Wang

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hetao ChenDepartment of Occupational and Environmental Health, School of Public Health, Tianjin Medical University, No. 22, Qixiangtai Road, Heping District, Tianjin, 300070, China.
Yu WangDepartment of Chemistry, Qiqihaer Medical College, Qiqihaer, 161006, Heilongjiang Province, China.
Tong WangDepartment of Occupational and Environmental Health, School of Public Health, Tianjin Medical University, No. 22, Qixiangtai Road, Heping District, Tianjin, 300070, China.
Dongxing ShiDepartment of Occupational and Environmental Health, School of Public Health, Tianjin Medical University, No. 22, Qixiangtai Road, Heping District, Tianjin, 300070, China.
Zengrong SunDepartment of Occupational and Environmental Health, School of Public Health, Tianjin Medical University, No. 22, Qixiangtai Road, Heping District, Tianjin, 300070, China.
Chunhui XiaDepartment of Chemistry, Qiqihaer Medical College, Qiqihaer, 161006, Heilongjiang Province, China. chunhuixia1969@sohu.com.
Baiqi WangDepartment of Occupational and Environmental Health, School of Public Health, Tianjin Medical University, No. 22, Qixiangtai Road, Heping District, Tianjin, 300070, China. wbqpaper@126.com.
Tianjin Medical University · CNQiqihar Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) is a serious disease to threat lives of women. Numerous studies have proved that BC originates from cancer stem cells (CSCs). But at present, no one approach can quickly and simply identify breast cancer stem cells (BCSCs) in solid tumor. Nanotechnology is probably able to realize this goal. But in study process, scientists find it seems that nanomaterials with one modality, such as magnetic resonance imaging (MRI) or fluorescence imaging (FI), have their own advantages and drawbacks. They cannot meet practical requirements in clinic. The nanoprobe combined MRI with FI modality is a promising tool to accurately detect desired cells with low amount in tissue. In this work, we briefly describe the MRI and FI development history, analyze advantages and disadvantages of nanomaterials with single modality in cancer cell detection. Then the application development of nanomaterials with dual-modality in cancer field is discussed. Finally, the obstacles and prospective of dual-modal nanoparticles in detection field of BCSCs are also pointed out in order to speed up clinical applications of nanoprobes.

Indexed as

AnimalsAntigens, NeoplasmBiomarkers, TumorBreast NeoplasmsContrast MediaErb-b2 Receptor Tyrosine KinasesFemaleGadolinium DTPAHumansImmunoconjugatesKi-67 AntigenMagnetic Resonance ImagingMiceNanoparticlesNeoplastic Stem CellsOptical ImagingAntigens, NeoplasmBiomarkers, TumorContrast MediaErbb2 protein, mouseErb-b2 Receptor Tyrosine KinasesGadolinium DTPAImmunoconjugatesKi-67 AntigenBreast cancerCancer stem cellsFluorescenceImagingMagnetic resonance

Identifiers

PMID27339420
PMCPMC4918029
OpenAlexW2467106210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.