ArticleEnvironmental health : a global access science source2016
Burden of disease resulting from lead exposure at toxic waste sites in Argentina, Mexico and Uruguay.
Article in Environmental health : a global access science source, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Lead Poisoning in the Americas: Sources, Regulations, Health Impacts, and Molecular Mechanisms.Journal of xenobiotics · 2025Review
- Prevalence and risk factors of elevated blood lead levels in 0-6-year-old children: a national cross-sectional study in China.Frontiers in public health · 2025Article
- Toward Heart-Healthy and Sustainable Cities: A Policy Statement From the American Heart Association.Circulation · 2024Review
- Secular trends in blood lead concentrations of school-age children in Montevideo, Uruguay from 2009 to 2019.Environmental pollution (Barking, Essex : 1987) · 2024Article
- The health impact of hazardous waste landfills and illegal dumps contaminated sites: An epidemiological study at ecological level in Italian Region.Frontiers in public health · 2023Article
- Estimating the burden of diseases attributable to lead exposure in the North Africa and Middle East region, 1990-2019: a systematic analysis for the Global Burden of Disease study 2019.Environmental health : a global access science source · 2022Article
- Maternal Blood Levels of Toxic and Essential Elements and Birth Outcomes in Argentina: The EMASAR Study.International journal of environmental research and public health · 2022Article
- Follow-Up of Elevated Blood Lead Levels and Sources in a Cohort of Children in Benin.International journal of environmental research and public health · 2020Article
- Probabilistic estimates of prenatal lead exposure at 195 toxic hotspots in low- and middle-income countries.Environmental research · 2020Article
- Lead Exposure in Low and Middle-Income Countries: Perspectives and Lessons on Patterns, Injustices, Economics, and Politics.International journal of environmental research and public health · 2018Article
- Evolution of human health risk based on EPA modeling for adults and children and pollution level of potentially toxic metals in Rafsanjan road dust: a case study in a semi-arid region, Iran.Environmental science and pollution research international · 2018Article
- Association between Blood Lead Levels and Delta-Aminolevulinic Acid Dehydratase in Pregnant Women.International journal of environmental research and public health · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThough lead contaminated waste sites have been widely researched in many high-income countries, their prevalence and associated health outcomes have not been well documented in low- and middle-income countries.
methodsUsing the well-established health metric disability-adjusted life year (DALY) and an exposure assessment method developed by Chatham-Stephens et al., we estimated the burden of disease resulting from exposure to lead at toxic waste sites in three Latin American countries in 2012: Argentina, Mexico and Uruguay. Toxic waste sites identified through Pure Earth's Toxic Sites Identification Program (TSIP) were screened for lead in both biological and environmental sample media. Estimates of cardiovascular disease incidence and other outcomes resulting from exposure to lead were utilized to estimate DALYs for each population at risk.
resultsApproximately 316,703 persons in three countries were at risk of exposure to pollutants at 129 unique sites identified through the TSIP database. Exposure to lead was estimated to result in between 51,432 and 115,042 DALYs, depending on the weighting factor used. The estimated burden of disease caused by exposure to lead in this analysis is comparable to that estimated for Parkinson's disease and bladder cancer in these countries.
conclusionsLead continues to pose a significant public health risk in Argentina, Mexico, and Uruguay. The burden of disease in these three countries is comparable with other widely recognized public health challenges. Knowledge of the relatively high number of DALYs associated with lead exposure may be used to generate support and funding for the remediation of toxic waste sites in these countries and others.
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